Question

One isoform of this enzyme requires lysyl-tRNA-3 to bind to a PBS before it can bind its substrate. Drugs that competitively inhibit this enzyme are normally given in pairs like tenofovir alafen·amide-emtrici·tabine. In certain “foamy” organisms, this enzyme is uniquely synthesized from a separate mRNA strand rather than a Gag precursor. The forced copy choice and the dynamic choice models describe a process that compensates for this enzyme’s high error rate and is called (*) template (-5[1])switching. (-5[2])An RNAse (10[1])H domain is present on this enzyme that, along with a protease and integrase, is transcribed from (10[1])the Pol gene. (10[1]-5[1])Gene (10[1])expression is frequently measured using a form (10[1])of PCR that relies on (-5[1])this enzyme’s (-5[1])ability to generate cDNA. (10[1]-5[2])For 10 points, name this central (-5[1])dogma-violating enzyme (10[2])that allows (10[2])retroviruses like HIV (10[1])to produce (10[1])DNA from (10[2])an RNA template. (10[1]) (10[4]0[6])■END■

ANSWER: reverse transcriptase [or RT]
<HK, Biology>
= Average correct buzz position

Buzzes

PlayerTeamOpponentBuzz PositionValue
Aisling SkeetDurhamWarwick74-5
Yashwanth BajjiMichigan A Ohio State B75-5
Aswath KaraiMSU A and FriendFarrellmagnetism75-5
Ketan PamurthyTAG Magnet: Taylor's VersionTexas A7710
Taiga ClarkeImperial BEdinburgh9410
Arya KarthikGeorgia Tech DGeorgia A97-5
Enoch YuenImperial ACambridge A9710
Tarun KotiEmory ATennessee A9810
Shiva TegullaZen and the Art of BuzzingArizona State10510
Logan HaynesGeorgia BGeorgia Tech B110-5
Rohan DalalGeorgia Tech CGeorgia Tech A112-5
Vedang SinghalNorth Carolina ANorth Carolina B116-5
Omer KeskinOxfordBirmingham116-5
IrisKenyon AKenyon B11610
Ted WarnerBristolCambridge B122-5
Aditya SharmaDukeNC State12410
Dennis YangMichigan B Ohio State A 12410
Isaac MammelMaryland AGeorge Washington B12610
Dimitris KalafatisTAMUTexas B12610
Sinecio MoralesJohns HopkinsMaryland B12910
Tianyu XuGeorgia Tech BGeorgia B13110
Faiz AhmedBirminghamOxford13310
Daniel MaFarrellmagnetismMSU A and Friend13310
Connor RonanSouth Carolina BSouth Carolina A13610
Benjamin McAvoy-BickfordNorth Carolina BNorth Carolina A1370
Arunn SankarGeorgia Tech AGeorgia Tech C13710
Jon GolanGeorgia AGeorgia Tech D13710
Rachel BenthamCambridge BBristol1370
Dillon PatelWarwickDurham1370
Wyatt RoderGeorgetownGeorge Washington A1370
Nick LaneGeorge Washington AGeorgetown1370
Jacob GoodsonOhio State BMichigan A 1370
Coby TranGanon Evans Fan ClubBoston College13710
Pablo LloydHCCTexas C13710