One isoform of this enzyme requires lysyl-tRNA-3 to bind to a PBS before it can bind its substrate. Drugs that competitively inhibit this enzyme are normally given in pairs like tenofovir (15[1])alafen·amide-emtrici·tabine. (15[1])In certain “foamy” organisms, this enzyme is uniquely synthesized from a separate mRNA strand rather than a Gag precursor. The (-5[1])forced copy choice and the dynamic choice models describe a process (15[1])that compensates for this enzyme’s high error rate and (15[1])is called (*) template switching. (-5[1])An RNAse H (-5[1])domain is present on this enzyme which, along with a protease and integrase, are transcribed from the (10[1])pol (-5[1])gene. (10[1])Gene expression (10[1])is (-5[1])frequently measured using a variant of PCR reliant on this enzyme’s ability to generate cDNA. For 10 points, name (10[1])this central (10[1])dogma-violating enzyme that allows retroviruses like HIV to produce DNA (10[1])from an RNA template. (10[2]0[5])■END■