Question

One isoform of this enzyme requires lysyl-tRNA-3 to bind to a PBS before it can bind its substrate. Drugs that competitively inhibit this enzyme are normally given in pairs like tenofovir alafen·amide-emtrici·tabine. In certain “foamy” organisms, this enzyme is uniquely synthesized from a separate mRNA strand rather than a Gag precursor. The forced copy choice and the dynamic choice models describe a process (15[1])that compensates for this enzyme’s high error rate and is called (*) template switching. An RNAse H domain is present on this enzyme which, along with a protease and integrase, are transcribed from the pol gene. Gene expression (10[1])is frequently measured using a variant of PCR reliant on this enzyme’s ability to generate cDNA. For 10 points, name this central dogma-violating enzyme that allows retroviruses like HIV to produce DNA from an RNA template. (0[2])■END■

ANSWER: reverse transcriptase [or RT]
<HK, Biology>
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PlayerTeamOpponentBuzz PositionValue
Maude-Sophie LockmanOttawa AMcDouble West-Carleton6215
Raymond ChenToronto Ray of Sun in the SkyOttawa C9910
Ishan JoshiOttawa BWaterloo1360
Michael DuWaterlooOttawa B1360

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2023 ARCADIA at UC BerkeleyPremiereY2100%50%0%83.00
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