Question

One isoform of this enzyme requires lysyl-tRNA-3 to bind to a PBS before it can bind its substrate. Drugs that competitively inhibit this enzyme are normally given in pairs like tenofovir alafen·amide-emtrici·tabine. In certain “foamy” organisms, this enzyme is uniquely synthesized from a separate mRNA strand rather than a Gag precursor. The (-5[1])forced copy choice and the dynamic choice models describe a process that compensates for this enzyme’s high error rate and is called (*) template switching. An RNAse H (-5[1])domain is present on this enzyme which, along with a protease and integrase, are transcribed from the pol gene. Gene expression is frequently measured using a variant of PCR reliant on this enzyme’s ability to generate cDNA. For 10 points, name this central dogma-violating enzyme that allows retroviruses like HIV to produce DNA from an RNA template. (10[1]0[1])■END■

ANSWER: reverse transcriptase [or RT]
<HK, Biology>
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Buzzes

PlayerTeamOpponentBuzz PositionValue
Darryl WangSyracuse+RochesterCornell R51-5
Cade ReinbergerRITCornell MATLAB78-5
Nathan ZhangCornell MATLABRIT1360
Richard NiuCornell RSyracuse+Rochester13610

Summary

2023 ARCADIA at UC BerkeleyPremiereY2100%50%0%83.00
2023 ARCADIA at Carleton UniversityPremiereY367%33%0%80.50
2023 ARCADIA at Claremont CollegesPremiereY10%0%100%0.00
2023 ARCADIA at IndianaPremiereY580%20%40%101.75
2023 ARCADIA at RITPremiereY250%0%100%136.00
2023 ARCADIA at WUSTLPremiereY3100%33%0%86.00