Four of these compounds are used as probes to evaluate enzyme activity in the so-called “Cooperstown cocktail.” Assays for these compounds often calculate their SSMD before subjecting them to QSAR modeling. The acronym ADME describes the kinetics of these compounds, which are characterized by Lipinski’s rule of five. (10[1])Cytochrome P450 monooxygenases modify these compounds (10[1])in the first phase of their metabolism. (10[2])The (10[1])first-pass effect reduces the bioavailability (10[1])of these compounds. (10[1])High-throughput screening is used in the “discovery” of these compounds, whose potency is given by the EC50. These compounds must pass Phase III clinical trials before receiving (10[1])regulatory approval by the FDA. For 10 points, name these compounds studied in pharmacology. (10[1])■END■