Question

Assays for measuring the activity of this compound based on BRET and FRET methods include CAMYEL and FlCRhR (10[1])(“flicker”). By forcing one enzyme to bind to calmodulin, a virulence factor produced by members of the genus Bordetella increases levels of this compound. The enzyme that produces this compound can be stimulated using Forskolin, and is activated by the A subunit of cholera toxin, which increases intracellular levels of this compound by over 100-fold. Low glucose levels cause this (-5[1])molecule to allosterically bind (10[1])to CRP (-5[1])as part of (10[1])a positive regulation mechanism. Phosphodiesterases most commonly act on this compound, which is necessary (10[1])for the activity of protein kinase A. (10[2])For 10 points, name this secondary messenger molecule made from ATP by adenylyl cyclase. (0[2])■END■ (10[1]0[1])

ANSWER: cyclic AMP [or cAMP; or cyclic adenosine monophosphate; prompt on AMP]
<MS, Biology>
= Average correct buzz position

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Summary

California2025-02-01Y3100%0%0%84.67
Great Lakes2025-02-01Y580%0%20%98.25
Lower Mid-Atlantic2025-02-01Y683%0%50%105.60
Midwest2025-02-01Y6100%0%17%84.33
North2025-02-01Y333%0%33%121.00
Overflow2025-02-01Y580%0%60%89.50
Pacific Northwest2025-02-01Y2100%0%50%107.50
South Central2025-02-01Y2100%0%0%92.50
Southeast2025-02-01Y475%0%50%119.67
UK2025-02-01Y1070%0%20%87.71
Upper Mid-Atlantic2025-02-01Y875%0%25%92.17
Upstate NY2025-02-01Y367%0%0%111.00

Buzzes

PlayerTeamOpponentBuzz PositionValue
Oscar DespardCambridge AOxford B1710
Cormac BeirneLSEImperial B76-5
Delia CropperOxford AWarwick B8010
Joel DickerSouthampton BNYU C82-5
James ByrneBristolSheffield8510
Ben LaFondCambridge BCambridge D9910
Arvin BoraghiCambridge CCambridge E10610
Adsayan GaneshWarwick AManchester10610
Zayyan MahmoodSouthampton AOxford C1200
Benjamin LiuOxford CSouthampton A1200
Justin LeeImperial ADurham12110
Jacob Hardin-BernhardtNYU CSouthampton B1210