Question

Assays for measuring the activity of this compound based on BRET and FRET methods include CAMYEL and FlCRhR (“flicker”). By forcing one enzyme to bind to calmodulin, a virulence factor produced by members of the genus Bordetella increases levels of this compound. The enzyme that produces this compound can be stimulated using Forskolin, (10[1])and is activated by the A subunit of cholera toxin, which increases intracellular levels of this compound by over 100-fold. Low glucose levels cause this molecule to allosterically bind to CRP as part of a positive regulation mechanism. (-5[1])Phosphodiesterases most commonly act on this compound, which is necessary for the activity of protein kinase A. (-5[1])For 10 points, name this secondary messenger molecule (-5[1])made (10[1])from ATP by adenylyl cyclase. (10[1])■END■ (10[2]0[2])

ANSWER: cyclic AMP [or cAMP; or cyclic adenosine monophosphate; prompt on AMP]
<MS, Biology>
= Average correct buzz position

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Buzzes

PlayerTeamOpponentBuzz PositionValue
Jacob EgolDukeWilliam & Mary5110
Connor RonanSouth CarolinaVirginia Tech A89-5
Michael EngUNC CLiberty B106-5
Sachin PoobalasinghamWake ForestVirginia A114-5
Rasheeq AzadUNC BLiberty A11510
Ilyas ChoukriVirginia Tech ASouth Carolina12010
Samuel MillerLiberty BUNC C1210
Alexandra KnightLiberty CUNC D12110
Jeffrey AustinUNC DLiberty C1210
Joseph ChambersVirginia AWake Forest12110

Summary

California2025-02-01Y3100%0%0%84.67
Great Lakes2025-02-01Y580%0%20%98.25
Lower Mid-Atlantic2025-02-01Y683%0%50%105.60
Midwest2025-02-01Y6100%0%17%84.33
North2025-02-01Y333%0%33%121.00
Overflow2025-02-01Y580%0%60%89.50
Pacific Northwest2025-02-01Y2100%0%50%107.50
South Central2025-02-01Y2100%0%0%92.50
Southeast2025-02-01Y475%0%50%119.67
UK2025-02-01Y1070%0%20%87.71
Upper Mid-Atlantic2025-02-01Y875%0%25%92.17
Upstate NY2025-02-01Y367%0%0%111.00