Question

Assays for measuring the activity of this compound based on BRET and FRET methods include CAMYEL and FlCRhR (10[1])(“flicker”). By forcing one enzyme to bind to calmodulin, (-5[1])a virulence factor (-5[1])produced by members of the genus Bordetella increases levels of this compound. (10[2])The enzyme that produces this compound can be stimulated using Forskolin, (10[1]-5[1])and is (10[1])activated by the A (10[1])subunit of (10[1])cholera toxin, (10[2])which increases intracellular (10[2])levels of this (10[1])compound by over 100-fold. (10[1])Low glucose levels cause this (-5[1])molecule to allosterically bind (10[1])to CRP (-5[3])as part (-5[1])of (10[1])a (-5[1])positive (10[1])regulation mechanism. (-5[1])Phosphodiesterases most commonly (-5[1])act on (10[1])this compound, which (10[1])is necessary (10[1])for the activity of protein kinase (10[1])A. (10[2]-5[1])For 10 points, name this secondary (-5[1])messenger molecule (10[1]-5[1])made (10[1])from ATP (10[5]-5[1])by (10[1])adenylyl (10[1]-5[1])cyclase. (10[1]0[2])■END■ (10[13]0[11])

ANSWER: cyclic AMP [or cAMP; or cyclic adenosine monophosphate; prompt on AMP]
<MS, Biology>
= Average correct buzz position

Summary

California2025-02-01Y3100%0%0%84.67
Great Lakes2025-02-01Y580%0%20%98.25
Lower Mid-Atlantic2025-02-01Y683%0%50%105.60
Midwest2025-02-01Y6100%0%17%84.33
North2025-02-01Y333%0%33%121.00
Overflow2025-02-01Y580%0%60%89.50
Pacific Northwest2025-02-01Y2100%0%50%107.50
South Central2025-02-01Y2100%0%0%92.50
Southeast2025-02-01Y475%0%50%119.67
UK2025-02-01Y1070%0%20%87.71
Upper Mid-Atlantic2025-02-01Y875%0%25%92.17
Upstate NY2025-02-01Y367%0%0%111.00

Buzzes

PlayerTeamOpponentBuzz PositionValue
Oscar DespardCambridge AOxford B1710
Rohan DalalGeorgia Tech CAlabama A25-5
Noah ChenColumbia BHaverford B28-5
Collin NadarajahWashU AIllinois C4010
Andrew WangIllinois AIndiana A4010
Jacob EgolDukeWilliam & Mary5110
Sharath NarayanNorthwestern AGeorgetown B51-5
Richard NiuCornell BColumbia C5310
Allan LeeStanford BGeorgetown A5710
Stan MelkumianPurdueNorthwestern B5910
Yashwanth BajjiMichigan AMichigan State6110
Sinecio MoralesJohns Hopkins ARutgers A6110
Swapnil GargUC Berkeley AClaremont B6410
Bryan UgazASUTexas B6410
Adam FineChicago AChicago B6710
Rohan ShelkeUC Berkeley BUCSD7110
Cormac BeirneLSEImperial B76-5
Delia CropperOxford AWarwick B8010
Samarth RamChicago CMissouri82-5
Patrick BoyleNotre Dame CNotre Dame A82-5
Joel DickerSouthampton BNYU C82-5
Frederick Rivas-GiorgiYale AVassar A84-5
James ByrneBristolSheffield8510
Jonah HubertNotre Dame BIowa86-5
Saketh DontarajuNYU AJohn Jay College8710
Connor RonanSouth CarolinaVirginia Tech A89-5
Truman FillbrandtUW AAlberta92-5
Russell NipUBCUW B9410
Jayden KuCarnegie Mellon BMichigan D9710
Ben LaFondCambridge BCambridge D9910
Pranaav SenthilkumarCornell DESF A10510
Michael EngUNC CLiberty B106-5
Arvin BoraghiCambridge CCambridge E10610
Adsayan GaneshWarwick AManchester10610
Brina RatangeeVanderbilt ALouisville A112-5
Sachin PoobalasinghamWake ForestVirginia A114-5
Alexandria WyersGeorge Washington ANYU B11410
Rasheeq AzadUNC BLiberty A11510
Aditya PatnaikOhio State BKenyon117-5
David NiemanCarnegie Mellon AOhio State A11710
Yash MandaviaIllinois BIndiana B11710
Samir SarmaGeorgia Tech DTennessee A11710
Danny HanPenn AGeorge Washington B11710
Cade ReinbergerRIT ACornell C11710
Enina EdosomwanCase Western ACase Western B11810
Kevin ParkClaremont AUCLA11910
Will HuangWisconsin ACarleton119-5
Ilyas ChoukriVirginia Tech ASouth Carolina12010
Zayyan MahmoodSouthampton AOxford C1200
Benjamin LiuOxford CSouthampton A1200
Jeffrey AustinUNC DLiberty C1210
Samuel MillerLiberty BUNC C1210
Alexandra KnightLiberty CUNC D12110
Joseph ChambersVirginia AWake Forest12110
Braden BoothMissouriChicago C12110
Benny Feldman Chicago DMissouri S&T12110
Ian SaylorWisconsin BMinnesota B1210
Morgan BozemanMinnesota BWisconsin B1210
Henry BonWinona StateIowa State12110
Brielle RachIowaNotre Dame B12110
Stephen HeritageNotre Dame ANotre Dame C12110
Jonathan HoAlbertaUW A12110
Karan GurazadaTexas ATAMU12110
Virginia StewartAlabama AGeorgia Tech C12110
Beckett GilmoreLouisville AVanderbilt A1210
Arunn SankarGeorgia Tech BBruin A12110
Jacob Hardin-BernhardtNYU CSouthampton B1210
Justin LeeImperial ADurham12110
William BrokerHaverford BColumbia B1210
Sam MacchiVassar AYale A12110
Kaiden CareyPenn BMaryland B1210
Gus VanskikeMaryland BPenn B1210
Emilie MooreRIT BBinghamton A1210
Elijah O’Sick JohnsonBinghamton ARIT B1210