Assays for measuring the activity of this compound based on BRET and FRET methods include CAMYEL and FlCRhR (“flicker”). By forcing one enzyme to bind to calmodulin, a virulence factor produced by members of the genus Bordetella increases levels of this compound. The enzyme that produces this compound can be stimulated using Forskolin, and is activated by the A subunit of cholera toxin, (10[1])which increases intracellular levels of this compound by over 100-fold. Low glucose levels cause this molecule to allosterically bind to CRP as part of a positive regulation mechanism. Phosphodiesterases most commonly act on this compound, which (10[1])is necessary for the activity of protein kinase A. For 10 points, name this secondary messenger molecule made from ATP (10[1]-5[1])by (10[1])adenylyl cyclase. ■END■