Question

Anti-cancer drugs that disable enzymes that cause this chemical change include “type-1.5” inhibitors exemplified by vemurafenib (vem-yew-RAFF-in-ib). Two-component systems consist of a response regulator and an enzyme that causes this chemical change, which unusually acts specifically on (-5[1])histidine. This change is caused by the enzyme Aurora B, which is activated during (*) mitosis as part of this (10[1])change’s namesake cascade. Glycogen is broken down by an enzyme that causes this change to a terminal glucose. In proteins, this change normally only occurs to tyrosine, serine, and threonine. Enzymes that cause this change to the substrate, such as the JAK and MAPK families, are called (10[1])kinases. For 10 (10[1])points, name this chemical change that converts ADP (10[1])to ATP. (10[1]0[1])■END■

ANSWER: phosphorylation [accept word forms; prompt on kinase activity before “kinase” is read]
<Gerhardt Hinkle, Biology>
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Buzzes

PlayerTeamOpponentBuzz PositionValue
Sam MooreFoucault's PenndulumOld London Town36-5
Max Fitz-JamesFour Neg OmeletteBetrayed by Rita Izzatdust5510
Ewan MacAulayScottish, Irish, Both or NeitherYes, Moderator10210
Enoch Yuen3HK1MMEdinburgh10510
Max EspensenOld London TownFoucault's Penndulum11310
Andrew Rout10 Negs that Shook the QuizTabearnacle1150
Abigal TanTabearnacle10 Negs that Shook the Quiz11510

Summary

2023 Penn Bowl (Harvard)10/21/2023Y3100%0%33%97.00
2023 Penn Bowl (Mainsite)10/21/2023Y786%14%14%57.33
2023 Penn Bowl (Norcal)10/28/2023Y2100%0%0%61.50
2023 Penn Bowl (South Central)10/28/2023Y367%0%0%77.50
2023 Penn Bowl (UK)10/28/2023Y5100%0%20%98.00
2023 Penn Bowl @ Waterloo10/28/2023Y4100%0%0%86.00
2023 Penn Bowl @ UNC10/28/2023Y3100%0%0%79.33
2023 Penn Bowl @ FSU10/28/2023Y1100%0%0%58.00