Question

Anti-cancer drugs that disable enzymes that cause this chemical change include “type-1.5” inhibitors exemplified by vemurafenib (vem-yew-RAFF-in-ib). Two-component systems consist of a response regulator and an enzyme that causes this chemical change, which unusually acts specifically on histidine. This change is caused by the enzyme Aurora B, which is activated during (*) mitosis as part of this change’s namesake cascade. (10[1])Glycogen is broken down by an enzyme that causes this change to a terminal glucose. In proteins, this change normally only occurs to tyrosine, (10[1])serine, and threonine. Enzymes that cause this change to the substrate, such as the JAK and MAPK families, are called (10[2])kinases. For 10 points, name this chemical change that converts ADP to ATP. ■END■

ANSWER: phosphorylation [accept word forms; prompt on kinase activity before “kinase” is read]
<Gerhardt Hinkle, Biology>
= Average correct buzz position

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Buzzes

PlayerTeamOpponentBuzz PositionValue
Raymond ChenToronto RoflMixed-Affiliated Contingency, Off the Team & Absent: Wong, Adrian5810
Liam KusalikWaterloo HatsuneLibrary of Babel School of Continuing Studies8210
Marcus Forbes-GreeneToronto JoyToronto Weary10210
Maude-Sophie LockmanLa Clique du ChateauWaterloo Miku10210

Summary

2023 Penn Bowl (Harvard)10/21/2023Y3100%0%33%97.00
2023 Penn Bowl (Mainsite)10/21/2023Y786%14%14%57.33
2023 Penn Bowl (Norcal)10/28/2023Y2100%0%0%61.50
2023 Penn Bowl (South Central)10/28/2023Y367%0%0%77.50
2023 Penn Bowl (UK)10/28/2023Y5100%0%20%98.00
2023 Penn Bowl @ Waterloo10/28/2023Y4100%0%0%86.00
2023 Penn Bowl @ UNC10/28/2023Y3100%0%0%79.33
2023 Penn Bowl @ FSU10/28/2023Y1100%0%0%58.00