Question

Anti-cancer drugs that disable enzymes that cause this chemical change include “type-1.5” inhibitors exemplified by vemurafenib (vem-yew-RAFF-in-ib). Two-component systems consist of a response regulator and an enzyme that causes this chemical change, which unusually acts specifically on histidine. This change is caused by the enzyme Aurora B, which is activated during (*) mitosis as part of this change’s namesake cascade. (10[1])Glycogen is broken down by an enzyme that causes this change to a terminal glucose. In proteins, this change normally only occurs to tyrosine, serine, and threonine. Enzymes that cause this change to the substrate, such as the JAK and MAPK families, are called kinases. For 10 points, name this chemical change that converts ADP to ATP. ■END■

ANSWER: phosphorylation [accept word forms; prompt on kinase activity before “kinase” is read]
<Gerhardt Hinkle, Biology>
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Buzzes

PlayerTeamOpponentBuzz PositionValue
Graham CopeFlorida ANorth Florida5810

Summary

2023 Penn Bowl (Harvard)10/21/2023Y3100%0%33%97.00
2023 Penn Bowl (Mainsite)10/21/2023Y786%14%14%57.33
2023 Penn Bowl (Norcal)10/28/2023Y2100%0%0%61.50
2023 Penn Bowl (South Central)10/28/2023Y367%0%0%77.50
2023 Penn Bowl (UK)10/28/2023Y5100%0%20%98.00
2023 Penn Bowl @ Waterloo10/28/2023Y4100%0%0%86.00
2023 Penn Bowl @ UNC10/28/2023Y3100%0%0%79.33
2023 Penn Bowl @ FSU10/28/2023Y1100%0%0%58.00