Question

Anti-cancer drugs that disable enzymes that cause this chemical change include “type-1.5” inhibitors exemplified by vemurafenib (vem-yew-RAFF-in-ib). Two-component (15[1])systems consist of a response regulator and an enzyme that causes this chemical change, which unusually acts specifically on (-5[1])histidine. This change is caused by the enzyme Aurora B, which is activated during (10[1])(*) mitosis as part of this (10[1])change’s namesake (10[4])cascade. (10[2])Glycogen is broken down (10[1])by an (10[2])enzyme that (10[1])causes this change to a terminal (10[1])glucose. In (-5[1])proteins, this change normally only occurs to tyrosine, (10[1])serine, and threonine. Enzymes that cause this change to the substrate, such as the JAK and (10[1])MAPK (10[1])families, are called (10[4])kinases. For 10 (10[1])points, name this chemical change (-5[1])that converts ADP (10[1])to (10[1])ATP. (10[2]0[4])■END■

ANSWER: phosphorylation [accept word forms; prompt on kinase activity before “kinase” is read]
<Gerhardt Hinkle, Biology>
= Average correct buzz position

Summary

2023 Penn Bowl (Harvard)10/21/2023Y3100%0%33%97.00
2023 Penn Bowl (Mainsite)10/21/2023Y786%14%14%57.33
2023 Penn Bowl (Norcal)10/28/2023Y2100%0%0%61.50
2023 Penn Bowl (South Central)10/28/2023Y367%0%0%77.50
2023 Penn Bowl (UK)10/28/2023Y5100%0%20%98.00
2023 Penn Bowl @ Waterloo10/28/2023Y4100%0%0%86.00
2023 Penn Bowl @ UNC10/28/2023Y3100%0%0%79.33
2023 Penn Bowl @ FSU10/28/2023Y1100%0%0%58.00

Buzzes

PlayerTeamOpponentBuzz PositionValue
Moses KitakuleColumbia ACornell B1715
Sam MooreFoucault's PenndulumOld London Town36-5
David BassjhuCOlumbia B5010
Max Fitz-JamesFour Neg OmeletteBetrayed by Rita Izzatdust5510
Jasmine BaoSwarthmoreRutgers5710
Cade ReinbergerRITUMD B5710
EricStanfordBerkeley C5710
Oliver WuOklahoma ATexas C5710
Raymond ChenToronto RoflMixed-Affiliated Contingency, Off the Team & Absent: Wong, Adrian5810
Graham CopeFlorida ANorth Florida5810
Jeffrey FungHarvardMIT6210
Derrick LiuJHU BPitt6410
Rasheeq AsadUNC CUSC B6410
Shahar SchwartzBerkeley ABerkeley B6610
Vincent DuUNC AUNC B7210
Mason YuBrownBrandeis74-5
Liam KusalikWaterloo HatsuneLibrary of Babel School of Continuing Studies8210
Ryan HumphreyTexas BTexas A9810
Caleb KendrickUMD ACornell A9910
Marcus Forbes-GreeneToronto JoyToronto Weary10210
Maude-Sophie LockmanLa Clique du ChateauWaterloo Miku10210
Ewan MacAulayScottish, Irish, Both or NeitherYes, Moderator10210
Aditya SharmaDuke AUSC A10210
Enoch Yuen3HK1MMEdinburgh10510
Jerry VinokurovJohn Jay ANYU110-5
Max EspensenOld London TownFoucault's Penndulum11310
Tanner EustaceBrandeisBrown11410
Emir GulBoston CollegeTufts11510
Eshan PantNYUJohn Jay A1150
Christopher LloydOklahoma BRice1150
Evelina TcherniakRiceOklahoma B1150
Abigal TanTabearnacle10 Negs that Shook the Quiz11510
Andrew Rout10 Negs that Shook the QuizTabearnacle1150