Question

To study this disease, the Karmanos Institute at Wayne State University derived the MCF7 and MCF10A cell lines. Classification of this disease can be done using the Nottingham index or BI-RADS. A particularly aggressive form of this disease presents with an “orange peel” appearance from pressure (10[2])on Cooper’s ligaments. It’s not related to bones, but Paget’s disease often indicates an underlying case of this disease, which may involve dissection of the axillary lymph nodes and can be treated with SERMs like tamoxifen. (10[1]-5[1])The absence of HER2, (10[1])estrogen, and progesterone receptors characterize the “triple negative” form of this disease. Susceptibility (10[1])to this disease is increased by mutations in two genes named for it called BRCA (“bra-ka”) 1 (10[1])and 2. (10[1])For 10 points, name this type of cancer screened for by a mammogram. (10[1])■END■ (10[1])

ANSWER: breast cancer [accept triple negative breast cancer or inflammatory breast cancer or IBC; prompt on cancer until read]
<MS, Biology>
= Average correct buzz position

Back to tossups

Buzzes

PlayerTeamOpponentBuzz PositionValue
Noah ChenColumbia BYale A4510
Sinecio MoralesJohns Hopkins AMaryland A4510
Ryan RosenbergNYU ACornell B8110
Zaid AsifNYU BGeorge Washington B81-5
Ivvone ZhouPenn ARutgers A8510
Avery BarnettHaverford APenn B9810
Jerry VinokurovJohn Jay CollegeColumbia C11410
Alexandria WyersGeorge Washington AHaverford B11610
Samuel KassoverGeorge Washington BNYU B12910
Sam MacchiVassar AMaryland B13010

Summary

Florida2025-02-01Y3100%0%0%105.00
Great Lakes2025-02-01Y6100%0%17%92.67
Lower Mid-Atlantic2025-02-01Y6100%0%17%117.00
Midwest2025-02-01Y6100%0%0%64.33
North2025-02-01Y3100%0%0%113.33
Northeast2025-02-01Y5100%0%20%114.40
Overflow2025-02-01Y4100%0%25%93.25
Pacific Northwest2025-02-01Y2100%0%0%87.00
South Central2025-02-01Y2100%0%0%88.50
Southeast2025-02-01Y4100%0%0%88.00
Upper Mid-Atlantic2025-02-01Y9100%0%11%93.67
Upstate NY2025-02-01Y3100%0%0%101.00