To study this disease, the Karmanos Institute at Wayne State University (10[1]-5[1])derived the MCF7 and MCF10A cell lines. Classification of this disease can be done using the Nottingham index (10[1])or BI-RADS. (10[2])A particularly aggressive (10[1])form of this disease presents with an “orange peel” appearance (10[1])from pressure (10[2])on Cooper’s ligaments. (10[1])It’s not related to bones, but Paget’s disease (10[1])often (10[1])indicates an underlying case of this disease, which may involve dissection of the axillary lymph nodes and can be treated with SERMs (-5[1])like tamoxifen. (10[3]-5[2])The (10[1])absence of (10[1])HER2, (10[2]-5[1])estrogen, and (10[1])progesterone (10[3])receptors (10[2])characterize the “triple negative” form of this disease. (10[3])Susceptibility (10[1])to this disease (10[1])is increased by mutations in (10[1])two genes (10[2])named for it called (10[1])BRCA (10[2])(“bra-ka”) 1 (10[4])and 2. (10[5])For 10 points, (10[2])name this type of cancer screened for by a mammogram. (10[4])■END■ (10[8])