SAR405 regulates this process by inhibiting Vps34, which activates a protein complex containing MLST8 and PRAS40. HSC70 initiates one form of this process by binding to proteins with a KFERQ (“K-F-E-R-Q”) motif and directing them to a LAMP2A multimeric complex. That chaperone-mediated form of this process is important for regulating cells under mechanical stress like muscle cells. By phosphorylating ULK1, mTOR (“M-tor”) downregulates this process. A study of this process earned Yoshinori Ohsumi a Nobel Prize in 2016. In yeast, this process is regulated by ATG proteins, and may be induced via starvation. (-5[1])During this process, (-5[1])large vesicles bind to lysosomes, (-5[1])whose hydrolytic enzymes break down defective proteins and organelles. For 10 points, name this process in which a cell digests its own components. ■END■ (10[1]0[1])