This disease was shown to have increased correlation with celiac disease by studies following Dorothy Hansine Andersen’s research on how it affects the pancreas. This disease is treated by modulators like ivacaftor and lumacaftor. The A·B·C·C·7 gene codes for an ABC-class transporter for ions like thiocyanate whose malfunction is a hallmark of this disease. This disease is caused by a mutation in the first nucleotide-binding domain of a (*) transmembrane conductance regulator, in which phenyl·alanine 508 is deleted. (10[2])It’s not sickle cell anemia, (10[1])but heterozygous advantage from the mutation that causes this disease confers resistance against cholera. Abnormal salt levels in a sweat test are used to diagnose this autosomal recessive disease. (10[1])For 10 points, what genetic disease leads to a buildup of mucus? ■END■ (10[1])