This disease was shown to have increased correlation with celiac disease by studies following Dorothy Hansine Andersen’s research on how it affects the pancreas. This disease is treated by modulators like ivacaftor and lumacaftor. The A·B·C·C·7 gene codes for an ABC-class transporter for ions like thiocyanate whose malfunction is a hallmark of this disease. This disease is caused by a mutation in the first nucleotide-binding domain of a (*) transmembrane conductance regulator, in which phenyl·alanine 508 is deleted. It’s not sickle cell anemia, but heterozygous advantage from the mutation that causes this disease confers resistance against cholera. Abnormal salt levels in a sweat test are used to diagnose this autosomal recessive disease. For 10 points, what genetic disease leads to a buildup of mucus? ■END■
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Jacob Egol | Master and Margaritaville | 4 quizbowl pros go Virginia on North Carolina | 76 | 10 |
| Jonathan Shauf | Even in Blacksburg There I Am | Ashurbanipal’s Drag Race | 81 | -5 |
| Ryan Rosenberg | Adrianne Lenker 4 Nobel Lit Prize 2K65 | Somehow Paula Deen Returned | 106 | -5 |
| Vasa Clarke | Somehow Paula Deen Returned | Adrianne Lenker 4 Nobel Lit Prize 2K65 | 123 | 10 |
| Matt Weiner | Ashurbanipal’s Drag Race | Even in Blacksburg There I Am | 123 | 10 |
| 2025 PLAYTIME Online | 04/26/2025 | Y | 9 | 100% | 44% | 0% | 65.78 |
| 2024 PLAYTIME @ Harvard | 04/26/2025 | Y | 4 | 100% | 0% | 0% | 93.00 |
| 2024 PLAYTIME @ Virginia Tech | 07/11/2025 | Y | 3 | 100% | 0% | 67% | 107.33 |
| 2024 PLAYTIME @ UBC | 10/05/2024 | Y | 7 | 86% | 0% | 14% | 88.50 |
| 2024 PLAYTIME @ WashU | 10/12/2024 | Y | 6 | 100% | 0% | 17% | 86.67 |
| 2024 PLAYTIME @ JHU | 10/26/2024 | Y | 7 | 100% | 0% | 14% | 104.29 |
| 2025 PLAYTIME @ Northwest | 12/10/2024 | Y | 4 | 75% | 25% | 25% | 76.67 |
| 2025 PLAYTIME @ Claremont | 12/10/2024 | Y | 5 | 100% | 0% | 0% | 93.20 |
| 2025 PLAYTIME @ Florida | 12/10/2024 | Y | 3 | 100% | 0% | 0% | 70.33 |
| 2025 PLAYTIME @ CWRU | 12/10/2024 | Y | 5 | 100% | 0% | 0% | 78.60 |
| 2025 PLAYTIME @ Sheffield | 12/10/2024 | Y | 7 | 100% | 29% | 43% | 89.71 |