Question

In 2020, Amy Wood et. al. created a molecular probe derived from these molecules’ KLVFFAE region. The p24 family protein TMP21 regulates the production of these molecules. The Arctic mutation decreases levels of these molecules, in contrast to the higher levels found as a result of the Swedish mutation. The thioflavin Pittsburgh compound B is often used in PET scans to image these molecules. A form of angiopathy named for these molecules is often indicated by (*) congo red staining. Inheriting the epsilon-4 allele of the ApoE gene can lead to lower degradation of these molecules. Gamma-secretases (-5[1])form these molecules by cleaving APP. (-5[1])Large deposits of these molecules characterize a certain disease, along with the presence of neurofibrillary tangles. For 10 points, name these peptides whose deposits create (-5[1])namesake “plaques” characteristic of Alzheimer’s disease. ■END■ (10[2]0[1])

ANSWER: amyloid beta [or A-Beta; accept amyloid plaques; accept beta-amyloid; prompt on amyloid]
<Science - Biology>
= Average correct buzz position

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Buzzes

PlayerTeamOpponentBuzz PositionValue
Arvin BorgahiCambridgeDefying Suavity95-5
Sam MooreSimple VibesLimp Francekit101-5
Brendan BethlehemCien Años de QuizboledadGrzegorz Brzęczyszczykiewicz126-5
Daoud JacksonDefying SuavityCambridge13310
Michael WuGrzegorz BrzęczyszczykiewiczCien Años de Quizboledad1330
Oscar O'FlanaganLimp FrancekitSimple Vibes13310

Summary

2024 ARGOS @ Stanford02/22/2025Y3100%0%67%123.00
2024 ARGOS @ Brandeis03/22/2025Y367%33%67%98.00
2024 ARGOS Online03/22/2025Y3100%33%0%89.00
2024 ARGOS @ Chicago11/23/2024Y667%50%33%75.00
2024 ARGOS @ Columbia11/23/2024Y333%0%67%133.00
2024 ARGOS @ Christ's College12/14/2024Y367%0%100%133.00