In 2020, Amy Wood et. al. created a molecular probe derived from these molecules’ KLVFFAE region. The p24 family protein TMP21 regulates the production of these molecules. The Arctic mutation decreases levels of these molecules, in contrast to the higher levels found as a result of the Swedish mutation. The thioflavin Pittsburgh compound B is often used in PET scans to image these molecules. A form of angiopathy named for these molecules is often indicated by (*) congo red staining. Inheriting the epsilon-4 allele of the ApoE gene can lead to lower degradation of these molecules. Gamma-secretases form these molecules by cleaving APP. Large deposits of these molecules characterize a certain disease, along with the presence of neurofibrillary tangles. For 10 points, name these peptides whose deposits create namesake “plaques” characteristic of Alzheimer’s disease. ■END■
ANSWER: amyloid beta [or A-Beta; accept amyloid plaques; accept beta-amyloid; prompt on amyloid]
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= Average correct buzz position