This process can be modeled using a set of functions representing inside, outside, and surface coordinates in a geometric algorithm named for Ephraim Katchalski-Katzir. An “X-Score” evaluates the feasibility of this process by calculating three hydrophobic parameters associated with desolvation. An instance of this process correlates to a measurable but tiny increase in temperature in isothermal titration calorimetry. (-5[1])This process ends after application of imidazole during nickel-column affinity chromatography. When modeled computationally, this process is referred to as molecular docking. This process occurs between molecules (10[1])more strongly if their dissociation constants (10[1])are low. For 10 points, name this process in which a ligand and a receptor with high affinity for each other become attached. (10[1])■END■ (10[1]0[3])