This process can be modeled using a set of functions representing inside, outside, and surface coordinates in a geometric algorithm named for Ephraim Katchalski-Katzir. An “X-Score” evaluates the feasibility of this process by calculating three hydrophobic parameters associated with desolvation. An instance of this process correlates to a measurable but tiny increase in temperature in isothermal titration calorimetry. This process ends after application of imidazole during nickel-column affinity chromatography. When modeled computationally, this process is referred to as molecular docking. This process occurs between molecules more strongly if their dissociation constants are low. For 10 points, name this process in which a ligand and a receptor with high affinity for each other become attached. ■END■ (10[1])