Question
Description acceptable. PsychLight offers a cell-based platform to detect this property in cells through specific conformations of the 5-HT2A receptor. For 10 points each:
[10m] Name this property. The mouse head twitch response is an in vivo assay for this property of compounds that is often exhibited by tryptamines.
ANSWER: hallucinogenicity [accept descriptive equivalents]
[10e] The hallucinogens psilocybin and 5-MeO-DMT are currently in clinical trials for this psychiatric condition’s treatment-resistant form, where patients do not respond to traditional medications such as SSRIs.
ANSWER: depression
[10h] Some psychoplastogens, such as rapastinel and ketamine, act on this receptor that is inhibited by PCP and blocked by magnesium ions. This calcium channel present in neurons has glutamate and glycine receptors and is selectively activated by a namesake glutamate analogue.
ANSWER: NMDA receptor [or NMDAR; accept N-methyl-D-aspartic acid or N-methyl-D-aspartate]
<Vishal Kanigicherla, Biology>
Summary
| 2023 Penn Bowl @ Waterloo | 10/28/2023 | Y | 3 | 10.00 | 100% | 0% | 0% |
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