One ruler with this name was deemed a heretic after the mystic Catherine of Siena declared her “demonically misguided” (15[1])for failing to back Urban VI. After her husband Andrew was thrown from a window (15[1])with a rope (15[1])tied to his genitals, that ruler of this name faced annexation (15[1])by her brother-in-law, (-5[1])Louis the Great of Hungary. To absolve herself of murder charges, that ruler of this name sold (*) Avignon to the papacy (-5[1])for 80,000 florins. Both queens (-5[1])regnant of Naples (10[1])had this first name, (10[2]-5[2])as well as a ruler that was (10[1])confined to the Palace (10[1])of Tordesillas (10[3]-5[1])after the death (10[1])of her (10[2])husband, (10[3]-5[1])Philip (10[2])the Handsome. (10[2]-5[1])That (-5[1])ruler of this name was deemed mentally (10[1])unfit (10[2]-5[1])to rule (10[1])by her father Ferdinand II, (10[2]-5[1])leading (10[1])to the ascension (10[1])of her son Charles (-5[1])V. For 10 points, give this name of a Spanish queen with (10[1])the epithet “The Mad.” (0[1]-5[1])■END■ (10[7]0[7])