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One of these proteins from the T1R family possesses a VFT module that can close around glutamate. During homologous desensitization, examples of these proteins with phosphorylated tails are targeted for endocytosis after being bound to beta-arrestin. Robert Lefkowitz and Brian Kobilka were awarded a Nobel Prize for their research on one of these proteins that binds to epinephrine. Retinal acts as a chromophore in many light-sensitive kinds of these proteins named (*) opsins. A heterotrimeric complex induces adenylyl cyclase to synthesize cAMP following activation of one of these proteins. These proteins characteristically contain seven transmembrane alpha-helical regions. For 10 points, name these proteins that operate in conjunction with G-proteins to initiate signal transduction. ■END■
| 2025 Penn Bowl - Stanford | 10/25/25 | Y | 4 | 100% | 50% | 50% | 71.75 |
| 2025 Penn Bowl - Northwestern | 10/25/25 | Y | 4 | 50% | 50% | 50% | 36.00 |
| 2025 Penn Bowl - Mainsite (UPenn) | 11/01/25 | Y | 6 | 50% | 17% | 67% | 75.33 |
| 2025 Penn Bowl - BU | 11/01/25 | Y | 4 | 50% | 25% | 25% | 63.50 |
| 2025 Penn Bowl - CWRU | 11/01/25 | Y | 3 | 67% | 0% | 67% | 99.50 |
| 2025 Penn Bowl - UNC | 11/01/25 | Y | 2 | 50% | 50% | 50% | 57.00 |
| 2025 Penn Bowl - WashU | 11/01/25 | Y | 2 | 100% | 50% | 0% | 56.50 |
| 2025 Penn Bowl - Ottawa | 11/01/25 | Y | 7 | 43% | 14% | 43% | 78.67 |
| 2025 Penn Bowl - UK | 11/01/25 | Y | 9 | 33% | 22% | 33% | 83.33 |
| 2025 Penn Bowl - Online | 11/08/25 | Y | 2 | 50% | 0% | 50% | 112.00 |
| 2025 Penn Bowl - Murray State | 11/08/25 | Y | 2 | 0% | 0% | 100% | 0.00 |
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Eric Yang | Purdue A | Northwestern A | 35 | 15 |
| Rachel Fanous | Michigan A | Ohio State B | 37 | -5 |
| Aden Sun | UChicago A | Illinois | 37 | 15 |
| Jason Zhang | Toronto Operation PBSuccess | Queen's is monitoring the situation | 37 | 15 |
| Aditya Shivaswamy | JHU A | Mount Sinai | 40 | 15 |
| Allan Lee | Stanford A | In Search of Lost Clues | 40 | 15 |
| Paul Lee | WashU Bouba | VJ Edgecombe School of Interior Design - Edwardsville | 40 | 15 |
| Richard Niu | The best time to buzz was twenty clues ago. The second best time to buzz is now | Berkeley C | 42 | 15 |
| Andres Cordoba | Yale | MIT A | 53 | 15 |
| Aditya Sharma | Wise Duke | UNC B | 57 | 15 |
| Kelvin Ni | NYU B | Swarthmore | 58 | -5 |
| Collin Leck | Central Oklahoma | Texas A | 62 | -5 |
| Vinu Harihar | Berkeley B | Stanford B | 62 | -5 |
| Swapnil Garg | Berkeley A | Free Win | 65 | -5 |
| Ted Warner | Bristold | Alas poor Warwick, I knew him Edinburgh | 69 | 15 |
| Nathan Easow | why is it called a score clue if nobody scores points on it | Quiztian Bale in Ratman Begins | 69 | -5 |
| Vivek Sasse | Hail to the Sheaf | Coughing Baby | 69 | 15 |
| Ryan Rosenberg | NYU A | Maryland C | 71 | -5 |
| Aatreyo Bhattacharyya | abg academy | rusty shackleford | 73 | -5 |
| Maude-Sophie Lockman | Aweille Kevin Fan osti continue comme ça | McGill B | 73 | -5 |
| June Yin | WashU Kiki | Truman State | 73 | 10 |
| Mason Yu | Brown | MIT B | 74 | 10 |
| Jonathan Lau | Maryland A | Maryland B | 74 | 10 |
| Samarth Ram | UChicago B | UChicago C | 75 | -5 |
| Ewan MacAulay | Washed Scrubs | Knorr Stock Clue | 82 | -5 |
| Moses Kitakule | Columbia A | Columbia B | 86 | -5 |
| Victor Xu | Toronto E | McGill Fartlets | 86 | -5 |
| Matthew He | Texas B | Oklahoma | 87 | -5 |
| Beckett Pursey | Purdue B | Northwestern B | 87 | -5 |
| Tony Chen | Toronto G | Guelph perfomative male competition | 87 | 10 |
| Ilyas Choukri | VT A | UNC A | 87 | -5 |
| Cade Reinberger | RIT | Harvard | 87 | -5 |
| Pace Klein | CWRU | Pittsburgh | 87 | 10 |
| Aditya Patnaik | Ohio State A | Michigan B | 87 | -5 |
| Shahar Schwartz | Free Win | Berkeley A | 93 | 10 |
| Marianthe Dreisos | JHU B | John Jay | 95 | -5 |
| Daoud Jackson | To buzz is to be perceived | Penn and the Art of Tossup-Bonus cycle Maintenance | 100 | -5 |
| Halee Carey | Ottawa 67s | Toronto Sunshine Bubbles | 108 | -5 |
| Jacob Goodson | Ohio State B | Michigan A | 112 | 0 |
| Daniel Kim | Maryland C | NYU A | 112 | 0 |
| Ben Hellman | Swarthmore | NYU B | 112 | 0 |
| Owen Gilroy | Texas A | Central Oklahoma | 112 | 0 |
| Braxton Davis | New Young Whigs of America | Wake Up Paddington A Washington Mystery | 112 | 0 |
| Simarya Ahuja | Wake Up Paddington A Washington Mystery | New Young Whigs of America | 112 | 0 |
| Will Alston | rusty shackleford | abg academy | 112 | 10 |
| Jesse Chusing | #OpenToBuzz | Carleton A | 112 | 0 |
| Nicolaus Derikx | Carleton A | #OpenToBuzz | 112 | 0 |
| Ava Butler | McGill B | Aweille Kevin Fan osti continue comme ça | 112 | 0 |
| Raymond Wang | I've been running into you in my lead plumbocene what could have benzene | Brandeis | 112 | 0 |
| Nathaniel Martin | Brandeis | I've been running into you in my lead plumbocene what could have benzene | 112 | 0 |
| Zach Foster | 1. Wawa 2. Blank Street 151. Black Sheep at Kings Cross rail | Paul Quifford, or, It Was a Dark and Stormy Tournament | 112 | 0 |
| Charlie Lowman | Paul Quifford, or, It Was a Dark and Stormy Tournament | 1. Wawa 2. Blank Street 151. Black Sheep at Kings Cross rail | 112 | 0 |
| Oliver West | Galactic Ombudsmen | The Bit and the Penndulum | 112 | 0 |
| Gus Redding | The Bit and the Penndulum | Galactic Ombudsmen | 112 | 0 |
| Dillon Patel | Of Mice and Penn | question mark | 112 | 0 |
| Andrei Hui | question mark | Of Mice and Penn | 112 | 0 |
| Philip Jordan | Quiztian Bale in Ratman Begins | why is it called a score clue if nobody scores points on it | 112 | 0 |
| Nick Smemoe | UNC A | VT A | 112 | 0 |
| James McCurley | Harvard | RIT | 112 | 0 |
| Josh Koch | Michigan B | Ohio State A | 112 | 10 |
| Chauncey Lo | Columbia B | Columbia A | 112 | 10 |
| Jerry Vinokurov | John Jay | JHU B | 112 | 0 |
| Charlie Ruff | McGill Fartlets | Toronto E | 112 | 0 |
| Caleb Ott | Waterloo you are crooked | Toronto Murder on the Rider Express | 112 | 10 |
| Sean Gao | Toronto Sunshine Bubbles | Ottawa 67s | 112 | 0 |
| Danny Han | Stanford B | Berkeley B | 112 | 10 |
| Max Fitz-James | Burnaburiash's Lapis Lazuli | Chimp Brisket | 112 | 0 |
| Oscar O’Flanagan | Chimp Brisket | Burnaburiash's Lapis Lazuli | 112 | 0 |
| Sam Moore | Knorr Stock Clue | Washed Scrubs | 112 | 10 |
| Omer Keskin | Penn and the Art of Tossup-Bonus cycle Maintenance | To buzz is to be perceived | 112 | 0 |