Note to moderator: Read the answerline carefully. Filigree edges in these things are disconnected rather than removed to efficiently construct them in the “meta” version of a “St. Petersburg” tool. Breakpoint graphs identify synteny (“SIN-tuh-nee”) blocks and rearrangements in these things. The SPAdes tool builds these things using de Bruijn (“duh broyn”) graphs of k-mers for de novo assembly. The program MiniMap2 chains minimizers in these things to address quadratic slowdown in the Smith–Waterman algorithm. The Bowtie package uses a Burrows–Wheeler transform to align these things. Eugene Myers helped develop a search tool for these things called BLAST, and advocated for a “shotgun” method to map them, which can also be done using techniques developed by Illumina and Sanger. For 10 points, Celera competed with a project to identify the human version of what entities representing an organism’s genetic material? ■END■
ANSWER: genomes [accept DNA sequences or nucleic acid sequences or nucleotide sequences or genetic sequences or RNA sequences or protein sequences or polypeptide sequences; accept or DNA sequencing or RNA sequencing or protein sequencing; accept sequence alignments or alignments; accept BLAST until read; accept Human Genome Project; prompt on strings or queries or letters or words or text; prompt on DNA or RNA or genes or promoters or codons or proteins or polypeptides or nucleotides or nucleic acids by asking “what kind of data structures can be used to represent them?”]
<UCSD, Biology>
= Average correct buzz position