Prospective vaccines for this disease in clinical trials include ones named V180 and TV-003. prM and E proteins expressed by agents that cause this disease are targeted by the CYD-TDV vaccine. Low platelet count and NS1 antigens are detected in this disease’s febrile phase. (-5[1])Infection by one of four serotypes of an agent that causes this disease in hosts vaccinated against it often leads to stronger symptoms due to (*) antibody-dependent enhancement. Extreme joint pain experienced (-5[1])during this flaviviral disease led it to be nicknamed “breakbone fever.” Chikungunya, Zika, and this (-5[1])disease are the most prevalent diseases (-5[1])spread by (-5[1])the Aedes aegypti (“AY-deez ay-JIP-tye”) mosquito vector. For 10 points, name (-5[1])this disease whose “severe” form was once called a namesake hemorrhagic fever. ■END■ (10[2]0[6])