Prospective vaccines for this disease in clinical trials include ones named V180 and TV-003. prM and E proteins expressed by agents that cause this disease are targeted by the CYD-TDV vaccine. Low platelet count and NS1 antigens are detected in this disease’s febrile phase. Infection by one of four serotypes of an agent that causes this disease in hosts vaccinated against it often leads to stronger symptoms due to (*) antibody-dependent enhancement. (10[1])Extreme joint pain experienced (10[1])during this flaviviral disease led it to be nicknamed “breakbone fever.” Chikungunya, Zika, and this disease are the most prevalent diseases spread by the Aedes (-5[1])aegypti (-5[1])(“AY-deez ay-JIP-tye”) mosquito vector. For 10 points, name this disease whose “severe” form was once called a namesake hemorrhagic fever. ■END■ (10[1]0[1])