Question

Enzymes hydrolyzing these compounds are categorized as “retaining” or “inverting,” depending on whether one of its two catalytic carboxylates displays nucleophilicity. The transition-state analog Zanamivir mimics one of these compounds, allowing the drug to inhibit neuraminidase (“nur-ah-MIN-ah-dayz”) activity during influenza infections. In one process, these compounds link to a different larger molecule at N-X-S/T (“N-X-S-slash-T”) sequences. A gradient of one of these compounds is often used to separate macromolecules during (*) centrifugation. One form of these molecules containing a free aldehyde can be detected by Benedict’s reagent. These (10[1])compounds, which can be visualized using Haworth projections, are typically identified with the suffix -ose (10[1])(“O-S-E”). For 10 points, name these compounds that include mannose and glucose. ■END■

ANSWER: carbohydrates [accept saccharides or sugars; accept monosaccharides or disaccharides or polysaccharides or oligosaccharides; accept glycosides; accept glycans; accept uronic acids; accept aldoses; accept ketoses; accept hexoses; accept pentoses; prompt on sucrose with “sucrose is an example of what kind of compound?”; prompt on N-acetylneuraminic acid or Neu5Ac or NANA; prompt on sialic acids]
<Kane Nguyen, Chemistry>
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PlayerTeamOpponentBuzz PositionValue
William GoldenHoustonTexas B8410
Dimitris KalafatisTAMUTexas A9910

Summary

2024 Penn Bowl UNC10/26/2024Y3100%0%0%76.67
2024 Penn Bowl Florida10/26/2024Y2100%0%0%92.50
2024 Penn Bowl Harvard10/26/2024Y4100%25%0%73.75
2024 Penn Bowl UK10/26/2024Y5100%0%20%88.60
2024 Penn Bowl Berkeley11/02/2024Y2100%50%0%66.00
2024 Penn Bowl Mainsite11/02/2024Y3100%0%0%88.67
2024 Penn Bowl CWRU11/02/2024Y4100%0%0%99.00
2024 Penn Bowl Chicago11/02/2024Y8100%25%13%77.00
2024 Penn Bowl Texas11/02/2024Y2100%0%0%91.50