Question
Recently developed medications used to treat this condition work by imitating the neurosteroid allopregnanolone (AH-loh-PREG-nan-noh-lone”). For 10 points each:
[10h] Name this condition that, since 2019, can be treated using brexanolone (“BREKS-an-noh-lone”). Individuals suffering from this condition are often assigned a score of thirteen or more on the Edinburgh scale.
ANSWER: postpartum depression [or PPD; accept postnatal depression; accept perinatal depression; accept peripartum depression; prompt on depression]
[10e] Mothers suffering from postpartum depression can also be prescribed sertraline, an SSRI that works by inhibiting neurons from reuptaking this mood-regulating neurotransmitter.
ANSWER: serotonin [or 5-hydroxytryptamine or 5-HT; accept selective serotonin reuptake inhibitors]
[10m] In some cases, postpartum depression is caused by dysfunction in a CRH-induced signaling axis that ends at this structure. Most of the body’s catecholamines (“KAH-teh-KOH-lah-meenz”) are secreted from this structure’s medulla.
ANSWER: adrenal gland [prompt on HPA axis]
<Benjamin McAvoy-Bickford, Biology>
Summary
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