Question

A biomarker for this state is the successful staining of beta-galactosidase at a pH of 6. For 10 points each:
[10m] Name this cellular state. Both terminally differentiated cells and cells in this state are irreversibly stuck in the G0 phase.
ANSWER: cellular senescence [or senescent; accept senescence-associated beta-galactosidase; prompt on aging or aged]
[10e] Senescence is characterized by the gradual shortening and then disappearance of these sequences on the ends of chromosomes. Their shortening is linked to the Hayflick limit.
ANSWER: telomeres
[10h] Another quality of senescent cells is a pro-inflammatory phenotype named for and characterized by this process. IL-1 beta undergoes a non-classical form of this process and is therefore called “leaderless.”
ANSWER: secretion [accept word forms like secreting; accept non-classical or non-conventional secretion; accept senescence-associated secretory phenotype; prompt on word forms of translocation; prompt on protein targeting]
<Chen, Biology>

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2024 ESPN @ Chicago03/23/2024Y514.00100%40%0%
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Data

JJarylandThe Aum-Wein Drinchard by Amogh Tutuola010010
JinAh and Jordan from Wikiquizmnemonists1010020
Sandmännchen im HelikopterNJ TRANSit (and bobby i guess)010010
Naocissus and Geoldmond by Hermandrew HessechamPAIN and cornHELL in Columbia1010020
1.g4 Test MixtureParden the Interruption1010020
boy's jitches (ft. DMA)bruh010010