This organelle’s dysfunction can cause NARP, a form of retinitis pigmentosa with neurodegeneration. In 2016, John Zhang controversially performed the first successful “spindle transfer” to circumvent a disease of this organelle, creating the first three-parent baby. “Stroke-like episodes” and lactic acidosis name one multisystem disease of this organelle. A Gomori trichrome stain can diagnose diseases of this organelle like Kearns-Sayre Disease and (*) Leigh (“LEE”) Syndrome through the appearance of characteristic “ragged red fibers.” Diseases’ severity and age of onset are most likely to be affected by heteroplasmy when they involve this organelle’s dysfunction, as it replicates asexually and independently from other organelles. For 10 points, name this organelle that is passed on by maternal inheritance through its own DNA and performs oxidative phosphorylation to make ATP. ■END■
ANSWER: mitochondria [or mitochondrion]
<Science - Biology>
= Average correct buzz position