Question

This organelle’s dysfunction can cause NARP, a form of retinitis pigmentosa with neurodegeneration. In 2016, John Zhang controversially performed the first successful “spindle transfer” to circumvent a disease of this organelle, creating the first three-parent baby. (15[1])“Stroke-like episodes” and lactic acidosis name (15[1])one multisystem disease of this organelle. A Gomori trichrome stain can diagnose diseases of this organelle like Kearns-Sayre Disease and (15[1])(*) Leigh (“LEE”) Syndrome (10[2])through the appearance of characteristic “ragged (10[1])red fibers.” Diseases’ severity and age of onset are most likely to be affected by heteroplasmy when they involve this organelle’s dysfunction, as it replicates asexually and independently from other organelles. For 10 points, name this organelle that is passed on by maternal inheritance through its own DNA and performs oxidative phosphorylation to make ATP. ■END■

ANSWER: mitochondria [or mitochondrion]
<Science - Biology>
= Average correct buzz position

Back to tossups

Buzzes

PlayerTeamOpponentBuzz PositionValue
Zach JosephNotre DameBHSU Rebirth3515
Chris MannersBHSU ReFantaziohawk two of4115
Jeremy CummingsWashUThat Feeling When Knee Surgery Is in Five Days6115
Andrew UllspergerMusic to Help You Stop SmokingClown Squad6310
Michael HundiingWho is the Colleen Hoover of the Zulus?Northeast by Northwestern6310
Adam FineThe Love Song of J Alfred PrufRock and Roll All Nite (and Party Every Day)Clown Senpais6910

Summary

2024 ARGOS @ McMaster11/17/2024Y5100%0%0%92.40
2024 ARGOS @ Chicago11/23/2024Y6100%50%0%55.33
2024 ARGOS @ Columbia11/23/2024Y3100%33%0%82.00