Question

An S-to-N acyl shift occurs in a reaction involving an amine group on this molecule and a thioester, called native chemical ligation. The remarkable stability of cyclotides is due to a motif involving six instances of this molecule that shares its structure with a rotaxane, its namesake “knot.” An N-acetyl derivative of this (15[1])amino acid is used to treat Tylenol overdose because it is converted to glutathione in the liver. Papain and (*) caspases belong to a class of proteases named for this non-alcohol-containing amino acid. Beta-mercaptoethanol (10[1])denatures proteins by cleaving bonds formed between two instances of this amino acid, which (10[1])are an important part (10[1])of tertiary structure. For 10 points, disulfide bridges form between two instances of what amino acid whose one-letter code is C? ■END■ (10[2])

ANSWER: cysteine [prompt on C until read]
<VD, Chemistry>
= Average correct buzz position

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Buzzes

PlayerTeamOpponentBuzz PositionValue
Liam KusalikWaterloo AspidistraOttawa Absolomabsolomabsolom5215
Tony ChenToronto AToronto Disband the Club 2k248510
Caleb OttWaterloo BasicToronto B9910
Asha BasuMcGill AMcMaster ApocolocyntosisBidii10310
Joey SunToronto Chestnut Rice and KamehamehaCarleton A12510
Ishan JoshiToronto Metropolitan AWaterloo Cloze12510

Summary