The D-site loses this structure due to distortion by Glu and Asp side chains in the mechanism of lysozyme. The Zimmerman-Traxler model predicts the aldol reaction's stereochemistry by assuming the transition state has this specific structure and analyzing the steric interactions. Transition states with this structure are thermodynamically favored for [3+3]-rearrangements like the Claisen and (*) Cope rearrangements. The Newman projection for this conformation is fully staggered, while it is fully gauche for a different conformation that experiences "flagpole" interactions. Rings in this conformation can undergo a "flip" that places bulky substituents on one of the six equatorial positions to avoid steric hindrance. For 10 points, the boat conformation is contrasted with what stablest conformation of cyclohexane? ■END■
ANSWER: chair conformation [prompt on ring or cyclic structure; prompt on cyclohexane]
<JZ, Chemistry>
= Average correct buzz position