Question
In 2022, Joanna Moncrieff led a controversial umbrella review that claimed to find “no support for the hypothesis that depression is caused by” low levels of this molecule. For 10 points each:
[10e] Name this neurotransmitter whose reuptake is inhibited by SSRIs. Sleep, appetite, and mood are regulated by this neurotransmitter.
ANSWER: serotonin [or 5-hydroxytryptamine or 5-HT; accept selective serotonin reuptake inhibitors]
[10h] Most serotonin is produced by enterochromaffin cells, but it can also be produced by these cells that mediate light-touch sensations. These SA1 mechanoreceptors are contrasted with ones named for Ruffini, Pacini, and Meissner.
ANSWER: Merkel cells [or Merkel-Ranvier cells or Merkel disks nerve endings or Merkel’s disks or Merkel tactile endings or tactile epithelial cells; prompt on epithelial cells]
[10m] Because serotonin is also stored in and aids the function of these things, using SSRIs with blood thinners may be risky. Clopidogrel blocks activation of these things, which crosslink with fibrin during hemostasis.
ANSWER: platelets [or thrombocytes]
<Biology>
Summary
| 2024 ACF Winter at UC Berkeley | 2024-11-16 | Y | 3 | 16.67 | 100% | 67% | 0% |
| 2024 ACF Winter at Clemson | 2024-11-16 | Y | 7 | 20.00 | 100% | 71% | 29% |
| 2024 ACF Winter at Clemson | 2024-11-16 | Y | 7 | 11.43 | 0% | 14% | 100% |
| 2024 ACF Winter at Lehigh | 2024-11-16 | Y | 7 | 17.14 | 100% | 71% | 0% |
| 2024 ACF Winter at Northwestern | 2024-11-16 | Y | 9 | 16.67 | 100% | 56% | 11% |
| 2024 ACF Winter at Online | 2024-11-16 | Y | 8 | 13.75 | 100% | 25% | 13% |
| 2024 ACF Winter at Online | 2024-11-16 | Y | 3 | 23.33 | 67% | 100% | 67% |
| 2024 ACF Winter at Central Florida | 2024-11-16 | Y | 5 | 14.00 | 100% | 20% | 20% |
| 2024 ACF Winter at Oxford | 2024-11-16 | Y | 10 | 15.00 | 90% | 50% | 10% |
Data
| Imperial A | Bristol A | 10 | 0 | 0 | 10 |
| Warwick B | Bristol B | 0 | 0 | 10 | 10 |
| Cambridge B | Cambridge A | 10 | 0 | 10 | 20 |
| Oxford A | Cambridge C | 10 | 0 | 10 | 20 |
| Birmingham | Cambridge D | 10 | 10 | 10 | 30 |
| Edinburgh | LSE B | 10 | 0 | 10 | 20 |
| Southampton B | Imperial B | 10 | 0 | 0 | 10 |
| LSE A | Manchester | 10 | 0 | 0 | 10 |
| Oxford B | Warwick A | 10 | 0 | 0 | 10 |
| Vanderbilt | Durham B | 10 | 0 | 0 | 10 |