serotonin - 2024 ACF Winter

Question

In 2022, Joanna Moncrieff led a controversial umbrella review that claimed to find “no support for the hypothesis that depression is caused by” low levels of this molecule. For 10 points each:

[10e] Name this neurotransmitter whose reuptake is inhibited by SSRIs. Sleep, appetite, and mood are regulated by this neurotransmitter.

ANSWER: serotonin [or 5-hydroxytryptamine or 5-HT; accept selective serotonin reuptake inhibitors]

[10h] Most serotonin is produced by enterochromaffin cells, but it can also be produced by these cells that mediate light-touch sensations. These SA1 mechanoreceptors are contrasted with ones named for Ruffini, Pacini, and Meissner.

ANSWER: Merkel cells [or Merkel-Ranvier cells or Merkel disks nerve endings or Merkel’s disks or Merkel tactile endings or tactile epithelial cells; prompt on epithelial cells]

[10m] Because serotonin is also stored in and aids the function of these things, using SSRIs with blood thinners may be risky. Clopidogrel blocks activation of these things, which crosslink with fibrin during hemostasis.

ANSWER: platelets [or thrombocytes]

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Summary


2024 ACF Winter at UC Berkeley	2024-11-16	Y	3	16.67	100%	67%	0%
2024 ACF Winter at Clemson	2024-11-16	Y	7	20.00	100%	71%	29%
2024 ACF Winter at Clemson	2024-11-16	Y	7	11.43	0%	14%	100%
2024 ACF Winter at Lehigh	2024-11-16	Y	7	17.14	100%	71%	0%
2024 ACF Winter at Northwestern	2024-11-16	Y	9	16.67	100%	56%	11%
2024 ACF Winter at Online	2024-11-16	Y	8	13.75	100%	25%	13%
2024 ACF Winter at Online	2024-11-16	Y	3	23.33	67%	100%	67%
2024 ACF Winter at Central Florida	2024-11-16	Y	5	14.00	100%	20%	20%

Data


Berkeley A	Berkeley B	10	0	10	20
Stanford A	Stanford L	10	0	0	10
Berkeley C	Stanford M	10	0	10	20
Alabama A	Clemson A	0	0	10	10
Alabama A	Clemson A	0	0	0	0
Alabama A	Emory B	10	0	10	20
Alabama A	Emory B	10	0	0	10
Georgia Tech F	Clemson A	10	0	10	20
Emory A	Georgia Tech D	0	10	0	10
Emory A	Georgia Tech D	0	10	10	20
Emory A	Auburn A	10	10	0	20
Emory A	Auburn A	10	10	10	30
Georgia Tech B	Auburn A	0	0	10	10
Georgia Tech B	Auburn A	0	0	0	0
Georgia Tech B	Georgia Tech A	10	0	10	20
Georgia Tech B	Georgia Tech A	10	0	0	10
Georgia Tech C	Georgia Tech F	0	10	0	10
Georgia Tech C	Georgia Tech F	0	10	0	10
Georgia Tech C	Georgia A	10	10	0	20
Georgia Tech C	Georgia A	10	10	0	20
Georgia Tech D	Georgia Tech E	10	0	10	20
Tusculum A	Auburn C	10	0	10	20
Alabama A	Clemson A	0	10	10	20
Alabama A	Clemson A	0	10	0	10
Alabama A	Emory B	10	10	10	30
Alabama A	Emory B	10	10	0	20
Georgia Tech B	Auburn A	0	10	10	20
Georgia Tech B	Auburn A	0	10	0	10
Georgia Tech B	Georgia Tech A	10	10	10	30
Georgia Tech B	Georgia Tech A	10	10	0	20
Auburn C	Auburn B	0	10	0	10
Emory B	Georgia A	0	10	0	10
Georgia Tech C	Georgia Tech F	0	10	0	10
Georgia Tech C	Georgia Tech F	0	10	0	10
Georgia Tech C	Georgia A	10	10	0	20
Georgia Tech C	Georgia A	10	10	0	20
Emory A	Georgia Tech D	0	10	0	10
Emory A	Georgia Tech D	0	10	10	20
Emory A	Auburn A	10	10	0	20
Emory A	Auburn A	10	10	10	30
Georgia Tech A	Georgia Tech E	0	10	0	10
Johns Hopkins B	Bard A	10	0	10	20
Columbia B	Princeton A	10	0	10	20
Johns Hopkins A	Haverford A	10	0	10	20
Rowan A	Penn B	10	0	10	20
Penn State A	Lehigh	10	0	0	10
Rutgers A	Penn State B	10	0	0	10
Rutgers C	Penn A	10	0	10	20
Miami	WashU B	10	10	10	30
Purdue D	Indiana B	10	0	0	10
UIUC B	SIUE A	10	0	10	20
UChicago C	UChicago A	10	0	0	10
Purdue A	UChicago D	10	0	10	20
UIUC A	WashU D	10	0	10	20
UIUC C	Purdue B	10	0	0	10
Notre Dame	UIUC D	10	0	10	20
WashU C	Purdue C	10	0	0	10
WUSTL A	Central Oklahoma	10	10	10	30
WUSTL A	Central Oklahoma	10	10	10	30
WUSTL A	Central Oklahoma	10	10	10	30
WUSTL A	Central Oklahoma	10	10	10	30
Mississippi State	NYU B	10	0	10	20
Mississippi State	NYU B	10	0	0	10
Mississippi State	McGill E	10	0	10	20
Mississippi State	McGill E	10	0	0	10
Vassar A	Iowa	10	10	10	30
Vassar A	Iowa	10	10	0	20
Vassar A	Central Oklahoma	0	10	10	20
Vassar A	Central Oklahoma	0	10	0	10
Vassar B	Arkansas	10	0	0	10
WUSTL A	Central Oklahoma	10	10	10	30
WUSTL A	Central Oklahoma	10	10	10	30
WUSTL A	Central Oklahoma	10	10	10	30
WUSTL A	Central Oklahoma	10	10	10	30
Vassar A	Iowa	10	0	10	20
Vassar A	Iowa	10	0	0	10
Vassar A	Central Oklahoma	0	0	10	10
Vassar A	Central Oklahoma	0	0	0	0
McGill E	Texas A	10	0	0	10
Mississippi State	NYU B	10	0	10	20
Mississippi State	NYU B	10	0	0	10
Mississippi State	McGill E	10	0	10	20
Mississippi State	McGill E	10	0	0	10
NYU A	Texas D	10	0	0	10
Ole Miss	Texas C	10	0	10	20
Colorado College	Texas B	10	0	0	10
Florida Tech B	UCF A	10	0	0	10
UCF B	Florida Tech A	10	0	0	10
Florida State University A	UF D	10	0	0	10
UF B	UF E	10	10	10	30
UF F	UF A	10	0	0	10