Question

One of these ions is consumed during the reaction that primes adrenodoxin for mitochondrial P450 steroid hormone synthesis. Two of these ions are donated during the oxidative phase of the pentose phosphate pathway, forming a cofactor that can repurpose these ions for fatty acid synthesis. The conversion of pyruvate to lactate (-5[1])during fermentation results in the donation of one of these ions to a niacin-derived cofactor for use in glycolysis. (10[1])These ions are donated by cofactors like FADH2, NADPH, (-5[1])and NADH to induce reductions in metabolic (-5[1])pathways. Similarly to alkyl groups, this ion can “shift” to more highly substituted carbon atoms (10[2])during carbocation rearrangements. For 10 points, name this reducing anion, which consists of a hydrogen with a negative charge. (10[1]0[1])■END■ (10[3])

ANSWER: hydrides [or H− (“H-minus”); prompt on electrons or electron pairs by asking “what atom is the carrier for those electrons?”; prompt on hydrogen or H; prompt on NADH until read; prompt on NADPH until read]
<Chemistry>
= Average correct buzz position

Back to tossups

Buzzes

PlayerTeamOpponentBuzz PositionValue
Brendan BethlehemCambridge BOxford A50-5
Oscar DespardCambridge ABristol6910
Dillon PatelWarwickSheffield78-5
Alexander BakerOxford BCambridge C85-5
Justin LeeImperial AOxford C10010
Sam MooreDurham ADurham B10010
Taiga ClarkeImperial BKiel11910
Lyndsey HepworthSheffieldWarwick1190
Jacob RobertsonOxford ACambridge B12010
Parth JagtapEdinburghKCL12010
Andrei HuiCambridge COxford B12010