The position of these regions can be approximated with the Haley–Knott method, which outputs LOD (“lod”) values. Eric Lander modified MAPMAKER for a landmark paper with David Botstein on the statistical identification of these regions, which established them as concrete Mendelian factors. The PrediXcan tool uses a generalized version of these regions prefixed “e” as reference for a TWAS (“TEE-woss”). Marker-directed selection in cereals usually uses microsatellites that flank these regions instead of SNPs (“snips”). Inbreeding two parent lines in opposite directions is a major cost when mapping these regions with linkage analysis. Most agriculturally-relevant phenotypes have additive contributions from several of these regions, which contain candidate genes. For 10 points, name these DNA regions that produce continuous phenotypes like size and color. ■END■
ANSWER: quantitative trait loci [or QTLs or quantitative trait locus; accept eQTLs or expression quantitative trait locuses or xQTLs; prompt on genetic locus, genetic loci, trait-associated loci, susceptibility loci, risk loci, or trait loci] (H–K regression is sensitive to selective genotyping, which only samples from individuals with extreme phenotypes.)
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= Average correct buzz position