DNA topoisomerase - 2024 ACF Fall at Washington

Question

This class of enzymes is classified depending on whether they cause single or double-strand breaks. For 10 points each:

[10h] Identify this class of enzymes that relax supercoiled DNA to render it accessible for other enzymes. These proteins can be found ahead of the replication fork.

ANSWER: DNA topoisomerase [accept topoisomerase I or topoisomerase II, prompt on topo]

[10m] DNA replication is more complicated for this strand of DNA that has to be synthesized in short bursts. Okazaki fragments are found on this strand that are connected by DNA ligase (“lie-gase”).

ANSWER: lagging strand [reject “leading strand”]

[10e] As part of the central dogma, DNA is transcribed to form this molecule that undergoes translation into protein. Popular COVID vaccines like Pfizer’s included the messenger type of this molecule abbreviated “m.”

ANSWER: RNA [accept ribonucleic acid or mRNA or messenger RNA]

Back to bonuses

Summary


2024 ACF Fall at Cornell	fall	Y	2	15.00	100%	50%	0%
2024 ACF Fall at Ohio State	fall	Y	6	18.33	100%	67%	17%
2024 ACF Fall at Washington	fall	Y	3	16.67	100%	67%	0%
2024 ACF Fall at Georgia	fall	Y	5	24.00	100%	100%	40%
2024 ACF Fall at North Carolina	fall	Y	3	13.33	100%	33%	0%
2024 ACF Fall at Claremont Colleges	fall	Y	4	22.50	100%	75%	50%
2024 ACF Fall at Rutgers	fall	Y	4	20.00	100%	75%	25%
2024 ACF Fall at Illinois	fall	Y	6	23.33	100%	83%	50%

Data


Alberta	UBC A	10	10	20
UW Lust	UBC B	0	10	10
UW Sloth	UW Pride	10	10	20