This class of enzymes is classified depending on whether they cause single or double-strand breaks. For 10 points each:
[10h] Identify this class of enzymes that relax supercoiled DNA to render it accessible for other enzymes. These proteins can be found ahead of the replication fork.
ANSWER: DNA topoisomerase [accept topoisomerase I or topoisomerase II, prompt on topo]
[10m] DNA replication is more complicated for this strand of DNA that has to be synthesized in short bursts. Okazaki fragments are found on this strand that are connected by DNA ligase (“lie-gase”).
ANSWER: lagging strand [reject “leading strand”]
[10e] As part of the central dogma, DNA is transcribed to form this molecule that undergoes translation into protein. Popular COVID vaccines like Pfizer’s included the messenger type of this molecule abbreviated “m.”
ANSWER: RNA [accept ribonucleic acid or mRNA or messenger RNA]
<Biology>