Question
Modified versions of these compounds undergo poly•epoxidation followed by cyclization during the biosynthesis of ladder polyethers such as cigua•toxin, maito•toxin, and breve•toxin. For 10 points each:
[10h] Name these compounds used as precursors in the biosynthesis of many natural products, which consist of alternating CO and CH2 groups.
ANSWER: polyketides
[10e] The biosynthesis of polyketides through chain elongation by repeatedly attaching two-carbon units is very similar to the biosynthesis of these other chains, which can esterify with glycerin to form lipids.
ANSWER: fatty acids [reject “fats”]
[10m] In the typical biosynthesis of polyketides and fatty acids, the initiator is acetyl-CoA and the chain extender is this derivative of coenzyme A, which is based on a three-carbon acid even though only two are added to the chain.
ANSWER: malonyl-CoA
<Gerhardt Hinkle, Chemistry>
Summary
| 2023 Penn Bowl @ Waterloo | 10/28/2023 | Y | 4 | 10.00 | 100% | 0% | 0% |
| 2023 Penn Bowl @ FSU | 10/28/2023 | Y | 2 | 0.00 | 0% | 0% | 0% |
| 2023 Penn Bowl (Harvard) | 10/21/2023 | Y | 3 | 13.33 | 67% | 33% | 33% |
| 2023 Penn Bowl (Mainsite) | 10/21/2023 | Y | 7 | 8.57 | 86% | 0% | 0% |
| 2023 Penn Bowl (Norcal) | 10/28/2023 | Y | 2 | 5.00 | 50% | 0% | 0% |
| 2023 Penn Bowl (South Central) | 10/28/2023 | Y | 3 | 6.67 | 67% | 0% | 0% |
| 2023 Penn Bowl (UK) | 10/28/2023 | Y | 5 | 10.00 | 100% | 0% | 0% |
| 2023 Penn Bowl @ UNC | 10/28/2023 | Y | 3 | 13.33 | 100% | 0% | 33% |
Data
| Columbia B | Columbia A | 0 | 10 | 0 | 10 |
| UMD A | Cornell B | 0 | 10 | 0 | 10 |
| John Jay A | JHU B | 0 | 10 | 0 | 10 |
| UMD B | NYU | 0 | 10 | 0 | 10 |
| JHU A | Pitt | 0 | 10 | 0 | 10 |
| RIT | Swarthmore | 0 | 0 | 0 | 0 |
| Rutgers | Cornell A | 0 | 10 | 0 | 10 |