A cyclic peptide that damages mitochondria and stimulates this process consists of three repeats of the sequence “oxy-leucine, alanine, oxy-valine, valine.” This process occurs in a “cyclic” fashion in an idiopathic disorder described in section B3b of the Rome criteria. Excess occurrence of this process is the most common cause of Mallory-Weiss syndrome. Cereulide (“sear”-EE-you-lyde) stimulates this process by activating 5-HT3 receptors in a section of the area postrema called the (*) chemoreceptor trigger zone. Drugs like on·dan·se·tron and di·men·hy·drin·ate prevent this process, which is preceded by contraction of the antrum, relaxation of the fundus, and retro·peristalsis in the proximal small intestine. The term “emesis” (EM-iss-iss) refers to, for 10 points, what forcible expulsion of the contents of the upper GI tract? ■END■
ANSWER: vomiting [accept puking or throwing up; accept cyclic vomiting syndrome; accept emesis before “emesis”; prompt on nausea or retching by asking “what happens next?”]
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= Average correct buzz position