Question

An assay for this process links fluorescent markers to cleavage site peptides like DEVD and YVAD. Chloromethyl-X-rosamine derivatives are used to detect MOMP, a change in potential that often precedes this process. CARD domains help orient a protein complex named for this process into a seven-spoked wheel shape. The polymerase TdT attaches nucleotides to 3-prime nicked ends in the TUNEL assay, which detects this process. (10[1]-5[1])Annexin A5 labels cells undergoing this process by binding to phosphatidylserine (“FOSS-fuh-TIDE-ull-SEE-reen”) on their membrane surface. (10[1])In the “intrinsic” (10[1])pathway of this process, the release of cytochrome C (10[1])initiates (10[2])a cascade of caspases that leads to “laddering” of genomic DNA and ends with membrane blebbing and nuclear fragmentation. For 10 points, name this process of programmed cell death. ■END■ (10[3])

ANSWER: apoptosis [prompt on death or cell death or programmed cell death or PCD; reject “necrosis”]
<Biology>
= Average correct buzz position

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Buzzes

PlayerTeamOpponentBuzz PositionValue
Vishal KanigicherlaPenn APrinceton B6410
Richard NiuCornell CVassar64-5
Lydia TarekegnYale ARutgers B7910
Andrew MinagarYale BNYU B8210
Forrest WeintraubColumbia AYale C9110
Srikar VenkatesanPenn BHaverford9210
Aiden DartleyRutgers APrinceton A9210
Jack RadoColumbia BBard A12210
Ashish KumbhardareRowan AColumbia C12210
Thomas DoyleVassarCornell C12210

Summary

2023 ACF Winter @ Columbia11/11/2023Y9100%0%11%96.22