An assay for this process links fluorescent markers to cleavage site peptides like DEVD and YVAD. Chloromethyl-X-rosamine derivatives are used to detect MOMP, a change in potential that often precedes this process. CARD domains help orient a protein complex named for this process into a seven-spoked wheel shape. The polymerase TdT attaches nucleotides to 3-prime nicked ends in the TUNEL assay, which detects this process. Annexin A5 labels cells undergoing this process by binding to phosphatidylserine (“FOSS-fuh-TIDE-ull-SEE-reen”) on their membrane surface. In the “intrinsic” pathway of this process, the release of cytochrome C initiates a cascade of caspases that leads to “laddering” of genomic DNA and ends with membrane blebbing and nuclear fragmentation. For 10 points, name this process of programmed cell death. ■END■
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Richard Niu | Cornell C | Vassar | 64 | -5 |
| Vishal Kanigicherla | Penn A | Princeton B | 64 | 10 |
| Lydia Tarekegn | Yale A | Rutgers B | 79 | 10 |
| Andrew Minagar | Yale B | NYU B | 82 | 10 |
| Forrest Weintraub | Columbia A | Yale C | 91 | 10 |
| Aiden Dartley | Rutgers A | Princeton A | 92 | 10 |
| Srikar Venkatesan | Penn B | Haverford | 92 | 10 |
| Thomas Doyle | Vassar | Cornell C | 122 | 10 |
| Jack Rado | Columbia B | Bard A | 122 | 10 |
| Ashish Kumbhardare | Rowan A | Columbia C | 122 | 10 |