“Spreading factors” that degrade this molecule increase the motility of members of Clostridium (“claw-strid-ee-um”), Streptococcus (“strep-toh-kok-us”), and Staphylococcus (“staff-ih-loh-kok-us”) in tissue. Low molecular weight fragments of this molecule are pro-inflammatory and angiogenic, (-5[1])while high molecular weight types are immunosuppressive and anti-angiogenic. BX7B motifs bind this molecule in receptors like RHAMM (“ram”) and CD44 (“C-D-forty-four”), which mediates its rapid turnover. This molecule in the corona radiata is degraded by an enzyme (10[1])released during the acrosomal reaction. Fillers like Restylane (“rest-al-in”) and Juvederm (“joov-eh-derm”) consist mostly of this molecule, (-5[2])as do injections for knee (10[1])pain (-5[1])due to (-5[1])osteoarthritis. (-5[2])This (10[1])polymer consists of units of (-5[1])glucuronic acid and N-acetylglucosamine (10[2]-5[2])(“N-ah-SEE-til-glue-KOS-ah-meen”), and it is a main component of lubricants like synovial fluid. For 10 points, name this only non-sulfated glycosaminoglycan (10[2])(“gly-kos-ah-meen-oh-gly-can”) often included (10[1]-5[2])in “hydrating” skincare formulations. (10[1])■END■ (10[6]0[4])