The causative agent of this disease contains a pE88 plasmid encoding several ABC transporters. This disease may cause Risus sardonicus and more general (10[3]-5[1])opisthotonus (10[1])(“opp-is-THOT-uh-nuss”) also seen in cerebral palsy or strychnine poisoning. Exotoxins present in this disease (10[1])include a cholesterol-dependent hemolysin and a ganglioside-binding protein (-5[1])that cleaves synaptobrevin. (10[1]-5[2])Renshaw cells are inactivated by this disease, (10[1])which prevents the release (-5[1])of inhibitory neurotransmitters. (10[2]-5[4])It’s not botulism, (10[1]-5[1])but (10[1])this disease is caused (-5[1])by (10[1])a Clostridium (10[4])bacterium (10[6]-5[3])and has symptoms (10[2])that can (10[1])be (10[1])alleviated (10[2])by (10[1])benzodiazepines. A toxoid from this disease (-5[1])is included alongside diphtheria (10[1])and pertussis (10[6]-5[2])in the (10[1])Tdap (10[5]-5[1])vaccine. (10[7]-5[2])For (10[1])10 (-5[1])points, (10[4]-5[1])name this (10[1])disease (10[4])that (10[1])causes muscle (10[1])spasms (10[3]-5[1])associated (10[6]-5[1])with (10[1])exposure (10[2])to rusty (10[3])nails. (10[4])■END■ (10[25])