endoplasmic reticulum - 2025 Penn Bowl

Question

The first step of one form of glycosylation begins with the insertion of dolichol (“daw-lih-CALL”) phosphate into the membrane of this organelle. For 10 points each:

[10e] Name this organelle that processes and packages peptides to the Golgi apparatus. Ribosomes stud this organelle’s rough form.

ANSWER: endoplasmic reticulum [or ER; accept rough endoplasmic reticulum or RER]

[10m] After insertion into the ER membrane, enzymes attach NAG and this molecule onto dolichol to create an oligosaccharide. Proteins tagged with a derivative of this molecule are directed to a hydrolase-rich structure.

ANSWER: mannose [accept mannose-6-phosphate]

[10h] After being translocated to the lumen side, a transferase attaches the oligosaccharide to this residue to complete that kind of glycosylation. This residue, proline, and alanine name a conserved motif found in aquaporins.

ANSWER: asparagine [or Asn; prompt on N or N-linked glycosylation by asking “what residue does that letter stand for?”; prompt on NPA motifs]

Back to bonuses

Summary


2025 Penn Bowl - BU	11/01/25	Y	4	10.00	100%	0%	0%
2025 Penn Bowl - CWRU	11/01/25	Y	3	10.00	100%	0%	0%
2025 Penn Bowl - Mainsite (UPenn)	11/01/25	Y	6	18.33	100%	50%	33%
2025 Penn Bowl - Murray State	11/08/25	Y	2	15.00	100%	50%	0%
2025 Penn Bowl - Northwestern	10/25/25	Y	4	15.00	100%	25%	25%
2025 Penn Bowl - Online	11/08/25	Y	2	15.00	100%	50%	0%
2025 Penn Bowl - Ottawa	11/01/25	Y	7	15.71	100%	43%	14%
2025 Penn Bowl - Stanford	10/25/25	Y	4	25.00	100%	100%	50%
2025 Penn Bowl - UK	11/01/25	Y	9	13.33	100%	33%	0%
2025 Penn Bowl - UNC	11/01/25	Y	3	10.00	100%	0%	0%
2025 Penn Bowl - WashU	11/01/25	Y	2	15.00	100%	50%	0%

Data


MIT A	Brown	10	0	0	10
Harvard	I've been running into you in my lead plumbocene what could have benzene	10	0	0	10
MIT B	Yale	10	0	0	10
Brandeis	RIT	10	0	0	10
Michigan B	Pittsburgh	10	0	0	10
Michigan A	Ohio State A	10	0	0	10
Ohio State B	CWRU	10	0	0	10
Mount Sinai	Columbia A	10	10	0	20
JHU A	John Jay	10	10	10	30
Maryland A	JHU B	10	0	10	20
Swarthmore	Maryland B	10	10	0	20
NYU B	Maryland C	10	0	0	10
NYU A	Columbia B	10	0	0	10
Central Oklahoma	Texas B	10	0	0	10
Texas A	Oklahoma	10	10	0	20
Illinois	Indiana	10	10	10	30
Northwestern A	UChicago B	10	0	0	10
Northwestern B	UChicago A	10	0	0	10
Purdue B	Purdue A	10	0	0	10
abg academy	New Young Whigs of America	10	10	0	20
Wake Up Paddington A Washington Mystery	rusty shackleford	10	0	0	10
Aweille Kevin Fan osti continue comme ça	Ottawa 67s	10	0	0	10
Toronto Operation PBSuccess	Guelph perfomative male competition	10	10	0	20
Waterloo you are crooked	McGill B	10	10	0	20
Toronto Murder on the Rider Express	McGill Fartlets	10	0	0	10
Queen's is monitoring the situation	Toronto E	10	0	0	10
Toronto G	Carleton A	10	10	10	30
Toronto Sunshine Bubbles	#OpenToBuzz	10	0	0	10
Berkeley B	Berkeley A	10	10	10	30
Free Win	Berkeley C	10	10	0	20
In Search of Lost Clues	Stanford A	10	10	0	20
The best time to buzz was twenty clues ago. The second best time to buzz is now	Stanford B	10	10	10	30
Alas poor Warwick, I knew him Edinburgh	question mark	10	0	0	10
To buzz is to be perceived	Chimp Brisket	10	0	0	10
Galactic Ombudsmen	1. Wawa 2. Blank Street 151. Black Sheep at Kings Cross rail	10	0	0	10
Knorr Stock Clue	Penn and the Art of Tossup-Bonus cycle Maintenance	10	10	0	20
Hail to the Sheaf	Paul Quifford, or, It Was a Dark and Stormy Tournament	10	10	0	20
Quiztian Bale in Ratman Begins	Of Mice and Penn	10	0	0	10
The Bit and the Penndulum	Coughing Baby	10	0	0	10
Washed Scrubs	Burnaburiash's Lapis Lazuli	10	10	0	20
why is it called a score clue if nobody scores points on it	Bristold	10	0	0	10
Planck Sinatra	Wise Duke	10	0	0	10
UNC B	UNC A	10	0	0	10
VT A	VT B	10	0	0	10
Truman State	VJ Edgecombe School of Interior Design - Edwardsville	10	0	0	10
WashU Bouba	WashU Kiki	10	10	0	20