apoptosome - 2024 PLAYTIME

Question

CARD domains are self-activated after being bound by this structure. For 10 points each:

[10h] Name this structure formed from seven subunits of the protein Apaf-1. This structure’s function can be identified by an assay that labels 3-prime-hydroxyl termini of double-stranded DNA breaks.

ANSWER: apoptosome

[10m] CARD domains are named for the activation and recruitment of these enzymes, whose “cascade” mediates apoptosis.

ANSWER: caspases [accept caspase activation and recruitment domains; accept caspase cascade]

[10e] The six-helix structure of CARD domains are conserved in the ced-3 and ced-4 genes of this model organism. Sydney Brenner pioneered research on this nematode, which was the first multicellular organism to have its entire genome sequenced.

ANSWER: C. elegans [or Caenorhabditis elegans; prompt on Caenorhabditis]

<SM, Biology>

Back to bonuses

Summary


2025 PLAYTIME @ CWRU	12/10/2024	Y	5	8.00	60%	20%	0%
2025 PLAYTIME @ Claremont	12/10/2024	Y	5	12.00	100%	20%	0%
2025 PLAYTIME @ Florida	12/10/2024	Y	3	20.00	100%	67%	33%
2024 PLAYTIME @ Harvard	04/26/2025	Y	4	10.00	100%	0%	0%
2024 PLAYTIME @ JHU	10/26/2024	Y	8	3.75	25%	13%	0%
2025 PLAYTIME @ Northwest	12/10/2024	Y	4	2.50	25%	0%	0%
2025 PLAYTIME Online	04/26/2025	Y	9	14.44	89%	44%	11%
2025 PLAYTIME @ Sheffield	12/10/2024	Y	7	10.00	57%	29%	14%
2024 PLAYTIME @ UBC	10/05/2024	Y	8	11.25	75%	25%	13%
2024 PLAYTIME @ Virginia Tech	07/11/2025	Y	3	20.00	100%	67%	33%
2024 PLAYTIME @ WashU	10/12/2024	Y	6	18.33	100%	83%	0%

Data


Michigan B	Michigan C	0	0	10	10
Michigan A	Oberlin	0	10	10	20
Pittsburgh	Ohio State B	0	0	10	10
Ohio State C	Ohio State A	0	0	0	0
Michigan D	Ohio State D	0	0	0	0
Art of Premature Signaling	UCSB	0	0	10	10
Claremont A	Caltech	0	0	10	10
Claremont B	UCLA A	0	0	10	10
P.C.‚ Daniel‚ Michel‚ and Jason B	UCLA B	0	0	10	10
girl 15 whale i mean they	UCSD	0	10	10	20
Keeping Up With the Cardassians	Billy's Bastion	0	10	10	20
Edwin Laundrorat's Long-Lost Man Unclothès Rat Degrosses	Qin Shi Huang's Immortality Poison	10	10	10	30
BU	Belmont	0	0	10	10
Brown	Brandeis	0	0	10	10
RIT	Harvard	0	0	10	10
Lexington	MIT	0	0	10	10
Too much from you lately	Project2025BC: Make Assyria Great Again	0	0	10	10
Rutgers	CWRU	0	10	10	20
Maryland B	George Mason A	0	0	0	0
George Mason B	NYU B	0	0	0	0
George Washington	Johns Hopkins B	0	0	0	0
Haverford B	Georgetown	0	0	0	0
Johns Hopkins A	George Mason C	0	0	10	10
Catholic University of America	Maryland A	0	0	0	0
NYU C	NYU A	0	0	0	0
UW B	Arizona State University A	0	0	0	0
Monsieur Hulot's Academic Team	Egypt Airlines Haters	0	10	10	20
Gruh	Four Generalists in Search of a Power	0	0	10	10
Mike Dukakis Tank Battalion	Free Agents 1	10	10	10	30
2 Italians, 2 Poles, All Noles	Goober Gang	0	0	0	0
Illinois Orange	Mahjonng Masters	0	10	10	20
Notre Dame + Epic Games	mongeese	0	10	10	20
Quatumvirate	MSJ	0	0	10	10
evil women enjoyers	Trip-Hop Quizzer Tricky	0	0	10	10
Cambridge	Birmingham	0	0	10	10
Edinburgh	Imperial A	0	0	10	10
LSE	Sheffield	0	0	0	0
Imperial B	Lancaster	10	10	0	20
Sheffield B	Sheffield C	0	10	0	10
Warwick A	Manchester	0	0	10	10
Warwick B	Warwick C	0	0	10	10
Arizona State University B	South Dakota School of Mines	0	0	0	0
Auburn 2026	we need new names	0	0	10	10
McGill A	Waterloo C	0	0	10	10
Ottawa A	Toronto E	0	0	0	0
Waterloo A	Toronto A	0	10	10	20
Toronto C	Toronto B	10	10	10	30
Toronto D	McGill B	0	0	10	10
Toronto Metropolitan	Mac A	0	0	0	0
Guelph	UBC	0	0	10	10
Waterloo B	Simon Fraser	0	0	10	10
Adrianne Lenker 4 Nobel Lit Prize 2K65	Somehow Paula Deen Returned	0	10	10	20
Ashurbanipal’s Drag Race	Even in Blacksburg There I Am	0	0	10	10
Master and Margaritaville	4 quizbowl pros go Virginia on North Carolina	10	10	10	30
Alberta	UW A	0	0	10	10
Washington Connections	Carleton	0	0	0	0
Missouri	Iowa State	0	0	10	10
Chicago B	SIUE	0	10	10	20
Chicago A	Truman State	0	10	10	20
Illinois A	WashU Bulbasaur	0	10	10	20
WashU Charmander	Illinois C	0	10	10	20
Illinois B	WashU Squirtle	0	10	10	20