Question
The Luxembourg Institute of Health maintains a database of proteins involved in this process in humans. Through its interaction with RAB7A, Rubicon is one of the few known negative regulators of this process. Fluorescent dots of LC3 are used to confirm the presence of this process. VPS34 phosphorylates inositol phospholipid at the start of this process as part of the Beclin-1 complex after being activated by ULK kinases, which are downregulated by (*) mTOR. In yeast, this process is regulated by the ATG genes. The “macro” form of this process results in the formation of a double-membrane vesicle around cytoplasmic components, which fuses with a lysosome for degradation. Yoshinori Ohsumi won the 2016 Nobel Prize in Physiology for his work on this process. For 10 points, name this process where a cell recycles its own material. ■END■
ANSWER: autophagy [or autophagocytosis; accept macroautophagy; prompt on lysosome formation by asking, “what other process does that result in?”] (The organelle is the phagosome.)
<Science - Biology>
= Average correct buzz position
Summary
| 2024 ARGOS @ Stanford | 02/22/2025 | Y | 3 | 100% | 33% | 0% | 72.00 |
| 2024 ARGOS Online | 03/22/2025 | Y | 3 | 100% | 67% | 33% | 75.33 |
| 2024 ARGOS @ Brandeis | 03/22/2025 | Y | 3 | 100% | 0% | 0% | 118.00 |
| 2024 ARGOS @ McMaster | 11/17/2024 | Y | 5 | 100% | 20% | 40% | 106.40 |
| 2024 ARGOS @ Columbia | 11/23/2024 | Y | 3 | 33% | 0% | 67% | 135.00 |
| 2024 ARGOS @ Chicago | 11/23/2024 | Y | 6 | 83% | 33% | 0% | 90.00 |
| 2024 ARGOS @ Christ's College | 12/14/2024 | Y | 2 | 50% | 0% | 100% | 135.00 |
Buzzes
| Player | Team | Opponent | Buzz Position | Value |
|---|---|---|---|---|
| Kane Nguyen | I'd prefer to have the team name be Christensen et al. than anything that Erik cooks up | Communism is Soviet power plus the yassification of the whole country | 32 | -5 |
| Eric Mukherjee | CLEVELAND, THIS IS FOR YOU! | throw away your cards, rally in the streets | 43 | 15 |
| Munir Siddiqui | I wish it were possible to freeze time so I would never have to watch you retire | UBC | 48 | 15 |
| Maude-Sophie Lockman | as rational as the square root of two power bottoms | Simpson Agonistes: The Crisis of Donut | 49 | -5 |
| Raymond Chen | She Dicer On My Argonaute Till I RNA Interfere | The Only Existing Manuscript from A Clockwork Orange | 60 | 15 |
| Neil Gurram | A is for Amy Robsart who fell down the stairs | Stanford+ | 61 | 15 |
| Adam Fine | The Love Song of J Alfred PrufRock and Roll All Nite (and Party Every Day) | BHSU Rebirth | 65 | 15 |
| Michael Hundiing | Who is the Colleen Hoover of the Zulus? | Clown Senpais | 66 | 15 |
| Shahar Schwartz | Cry of the Common Loon | number of tang poems = 75 times number of lines in a shi = 100 times number of lines in a haiku | 72 | 10 |
| Caleb Ott | Tensei Shitara Flashcard Data Ken | You cannot go to Aarhus to see his peat-brown head / With eyes like ripening fruit | 78 | 10 |
| Derek Chen | Walston et. al. | just one more half-dot bro | 82 | -5 |
| Rohan Shelke | Berkeley | Where are the ACF Nationals recordings? | 83 | 10 |
| Adam Silverman | |madam| | Hu up Jinning they Tao | 84 | 10 |
| Andrew Wang | BHSU ReFantazio | WashU | 84 | 10 |
| Yashwanth Bajji | Clown Squad | hawk two of | 100 | 10 |
| Sky Hong | NJ TRANSit (and anwen | jeff mcneil #1 morningside heights fan club | 106 | -5 |
| Evan Ting | Aw we're so sorry to hear that maman died today, she gets five big booms | Thompson et al. | 106 | -5 |
| Sam Moore | Simple Vibes | Cambridge | 111 | -5 |
| Daoud Jackson | Defying Suavity | Cien Años de Quizboledad | 115 | -5 |
| Aaron Dos Remedios | Moderator Can't Neg me While in Alpha | Ryan Wesley Routh's 10 000 NATO-trained Afghan Quizbowlers | 124 | 10 |
| Walter Zhang | Import Pandas | Banned from ARGOS | 135 | 10 |
| Sam/Cypress Macchi | Pahkin' the Ahgo | "Powers a question on Stancyzk" that's a clown question bro | 135 | 0 |
| Jordan Brownstein | "Powers a question on Stancyzk" that's a clown question bro | Pahkin' the Ahgo | 135 | 10 |
| Matt Schiavone | Northeast by Northwestern | Notre Dame | 135 | 0 |
| Stephen Heritage | Notre Dame | Northeast by Northwestern | 135 | 0 |
| Andrew Ullsperger | Music to Help You Stop Smoking | That Feeling When Knee Surgery Is in Five Days | 135 | 10 |
| Arvin Borgahi | Cambridge | Simple Vibes | 135 | 0 |
| Joseph Krol | Cien Años de Quizboledad | Defying Suavity | 135 | 10 |
| Ryan Rosenberg | Cope is the thing with feathers | 12 Litres of Green Tea | 135 | 10 |
| Jeremy Tsai | just one more half-dot bro | Walston et. al. | 135 | 0 |
| Tony Chen | Simpson Agonistes: The Crisis of Donut | as rational as the square root of two power bottoms | 135 | 10 |
| Henry Atkins | Communism is Soviet power plus the yassification of the whole country | I'd prefer to have the team name be Christensen et al. than anything that Erik cooks up | 135 | 10 |
| Conor Thompson | Thompson et al. | Aw we're so sorry to hear that maman died today, she gets five big booms | 135 | 10 |